spacer
home > epc > spring 2009 > ediary time
PUBLICATIONS
European Pharmaceutical Contractor

eDiary Time

Back in the days of pen and paper clinical trials monitoring, something familiar but disconcerting caught my attention as I got out of the car. There in the next car sat a patient busy filling in his diary card with peak expiratory flow (PEF) readings and symptoms for the past month. Mentioning this to the investigating consultant, he called the patient in, commended him for having a complete diary, and then as he rubbed his finger over it, said, “oh dear the ink is still wet!” Having observed this, I concluded that there had to be a better way of recording diary data. The answer came in the early 1990s with the development of e-spirometric diaries. Chowienczyk et al compared paper versus electronic recording of spirometry data, demonstrating that 33 per cent of completed entries were either invented, mistimed or misread, and were often retrospectively entered (1). Since then, other studies have confirmed that paper diaries often contain invented data (2,3).


Read full article from PDF >>

Rate this article You must be a member of the site to make a vote.  
Average rating:
0
     

There are no comments in regards to this article.

 You must be a member of the site to make a comment.
spacer

Initially qualifying as an entomologist, Aleck Harrison swiftly moved from ‘bugs to drugs’ and spent 34 years with Boehringer Ingelheim Ltd. Evolving from CRA to managing international respiratory studies, he advised a number of companies on spirometric diary development. Having semiretired, he started the consultancy of AJH Partners (Contract Research and Consultancy). Amongst his recent activities, he has supported respiratory companies, including Vitalograph Ltd, with the introduction and development of their centralised spirometry system.

spacer
Aleck Harrison
spacer
spacer
Print this page
Send to a friend
Privacy statement
News and Press Releases

Turkish Cargo maintains its dual-terminal operations seamlessly

Completing the gradual transition process to Istanbul Airport, one of the largest airports of the world, the global air cargo brand Turkish Cargo maintains its dual-terminal operations with full capacity on 7/24 basis without any sales restriction.
More info >>

White Papers

The Flexible Factory Concept: A flexible bioprocessing platform to meet the changing needs of biomanufacturing

GE Healthcare Life Sciences

For the past several years, the biopharma industry has been buffeted by dynamic market conditions that are rapidly reshaping manufacturing requirements. These factors include: • The rise of small-market pharmaceuticals that do not require the production scale of the previous “blockbuster” drug model • Increased titers and process productivity that generate more bulk-product within a much smaller manufacturing footprint • The emergence of biosimilars and continued evolution of healthcare reform, which will increasingly pressure drug pricing and require greater cost discipline • Greater competition and shorter patent protection timelines, which will further ratchet up time-to-market pressures • Tighter capital markets that will create heightened scrutiny for all new investment projects
More info >>

 
Industry Events

CPhI & P-MEC India

26-28 November 2019, India Expo Centre, Greater Noida, Delhi NCR, India

As the pharma industry looks increasingly towards India forhigh quality, low   cost pharma solutions, CPhI & P-MEC Indiais the ideal event for companies wanting to pick up on the latest trends and innovations the market has to offer. At CPhI & P-MEC India, you will meet the movers and shakers from India’s pharma machinery, technology and ingredients industries, giving you a competitive advantage that will help grow your business.
More info >>

 

 

©2000-2011 Samedan Ltd.
Add to favourites

Print this page

Send to a friend
Privacy statement