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European Biopharmaceutical Review

Targeted Technology

By recognising the market value of a new class of bioelectronic medicine, which is based on biosensors, electronics, nanotechnology, and biotechnology research foundations, this article puts perspective forward on bringing the technology from lab to market. Here, a comprehensive review is provided on the progress and development of bioelectronic medicine in academia, clinical hospitals, and industrial settings.

‘Bioelectronics’ was first defined in 1991 as “the use of biological materials and biological architectures for information processing and new devices” (1). Furthermore, bioelectronics can be broadly elaborated as a fusion of electronics with biological systems where an electronic device facilitates in the transduction of signal from the biological systems to electrical device in the human body at a bioelectronic interface. R&D in bioelectronics has resulted in vital medical electronics devices, such as brain stimulators, glucose sensors, and pacemakers (2-4). This article will elaborate upon the current development of bioelectronics in academia and industry and, in addition, offer a future perspective with respect to the use of bioelectronic devices for precision medicine.

Bioelectronics in Precision Medicine

Interests in both clinical and fundamental research, with respect to personalised and precision medicine, are increasing. Personalised and precision medicine promises to revolutionise existing medical treatment. According to the Precision Medicine Initiative, precision medicine is defined as “an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person.” Research has established a bioelectronic ecosystem consisting of portable biosensors and biomedical nano-robots that combine health monitoring with medical therapy (5). Such bioelectronic devices offer distinct advantages towards precision medicine.

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Dr Deepak B Thimiri Govinda Raj holds a BTech in biotechnology from Bharathidasan University Trichy, India, and an ME in biotechnology from Birla Institute of Technology and Science, India. Deepak also has a PhD in biomedical sciences from KU Leuven, Belgium. Deepak is Co-Founder at DTCG® Consulting and Envirotransgene® Biosolutions Global. 

Prasanna Subramaniam has a BTech in biotechnology from Bharathidasan University Trichy, India, and an MTech in biopharmaceutical engineering and technology from Anna University, India. Prasanna has 12 years of experience in bioprocessing technology and biopharmaceutical operations. He is currently working as Deputy Manager at Biocon.

Dr Sri Saran Venkatachalam earned his BSc in applied sciences and MA of science in materials from Anna University, India. Sri also has a PhD in material science from the Institute of Electronics, Microelectronics, and Nanotechnology, France. He has 10 years of research and teaching experience in material science and electronics. Currently, he is an Assistant Professor at Bannari Amman Institute of Technology, India.

Dinh-Toi Chu PhD received a doctor of veterinary medicine degree at the Vietnam National University of Agriculture, Vietnam, an MA of biological science at the University of Ulsan, South Korea, and then a PhD in medicine at the Polish Academy of Sciences in Olsztyn and Medical University of Bialystok, Poland. Dinh-Toi has been a researcher and lecturer in immunology, cell biology, and animal pathology.
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Dr Deepak B Thimiri Govinda Raj
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Prasanna Subramaniam
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Dr Sri Saran Venkatachalam
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Dinh-Toi Chu PhD
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