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European Biopharmaceutical Review

Jewel Biomarkers Can Be Found By Digging in the Right Mine

Biomarkers can be fantastic diagnostic tools, especially for rare diseases (1:2,000 up to about 1:100,000) for which an accurate identification may even be lifesaving if identified early on. Literature and experts see biomarkers as cornerstones for the development of new therapeutic approaches.

The EMA and FDA are proponents of seeing the therapeutic effects achieved through biomarker-based ‘theragnostic’. Historically, surrogate biomarkers were accepted in the past (for example, haemoglobin A1c for diabetes). Nowadays, however, biomarkers closely linked to a sickness and potential therapeutic intervention are even more welcome.

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Professor Hermann Mascher, Bioanalytical Consultant and founder of pharm-analyt Labor, has more than 100 publications in peer-reviewed journals (and more than 230 cumulative impact factor). He is the inventor of three patents for biomarkers in the area of rare LSDs (Gaucher, NP-C, and metachromatic leukodystrophy) which could be sold.
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Professor Hermann Mascher
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