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European Biopharmaceutical Review
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The discovery of penicillin by Alexander Fleming in 1928 revolutionised medicine. This antibiotic soon became one of the most widely used in treating common bacterial infections, as well as pneumonia, tuberculosis, syphilis, and more (1). However, the Nobel Prize winner also predicted how an irresponsible use of penicillin could lead to the development of resistant bacteria, resulting in losing the antibiotic efficacy and death caused by a lack of alternative treatments. His concern has become a real-life scenario, affecting the medical sector and animal husbandry on a global scale.
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New study confirms that purity and type of coating biomaterials used in 2D cell culturing are crucial for efficient stem cell proliferation
Rousselot®, Darling Ingredients’ health brand and the global leader1 of collagen-based solutions, revealed the results of a new study which demonstrates that Rousselot’s ultra-pure GMP-grade2 gelatins outperformed standard non-endotoxin purified research grade gelatins and other coating materials in 2D cell culturing. Data demonstrate that endotoxin (lipopolysaccharide, LPS) levels and the nature of biomaterials used in cell coating have a significant impact on cell morphology and proliferation.
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Six Strategies to Stretch Your Limited Drug Supply for Clinical Studies
PCI Pharma Services
Bringing a new drug to market can be a heavy financial burden on any pharmaceutical company. It has become even more burdensome over the last several years as the industry pushes the boundaries of innovation. This is because newer, often more-complex therapies not only increase risk in drug development but also drive costs even higher. A recent analysis of the investment needed to develop a new prescription medicine shows the total cost can be as high as $2.6 billion (1). That number becomes even more staggering when you consider the fact that only about 12 percent of drug candidates that make it to Phase I testing are eventually approved by the FDA (2). The investment companies lose as a result may be too devastating to their bottom line to ever recover.
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