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European Biopharmaceutical Review

Putting Function First in Proteomics

The last few years have seen an enormous revival in protein science under the relatively new name of 'proteomics'. The term proteome was coined by Marc Wilkins in 1994, and is used to describe the entire protein complement of the genome. This can be further defined as the protein complement at any point in time - underlining the fact that proteins are complex, dynamic systems constantly changing in number and structure in response to physiological and environmental stimuli. Unlike traditional protein biochemistry, the science of proteomics generally refers to large-scale protein studies involving the high throughput screening and identification of novel proteins. A key aim of proteomics is to uncover the function of novel proteins - so providing possible new targets for drug intervention. Surface plasmon resonance (SPR) technology not only provides a means of isolating novel proteins, but also of uncovering their functional properties.


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By Stefan Lfs, Vice President and Chief Scientific Officer at Biacore AB

Stefan Lfs holds a PhD and BSc in Organic Chemistry. He has extensive technical and scientific experience in the development and commercialisation of bioanalytical instrumentation at Biacore AB, having worked for the company since 1985. He has been deeply involved in the development of Biacore's sensor chip chemistry and applications. Recently appointed Chief Scientific Officer, he has responsibility for technical development projects, external scientific collaborations and technical aspects on the IPR portfolio. Prior to this role, Dr Lfs was Director of Biacore's Biochemistry and Chemistry department within R&D.
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Stefan Lfs
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