samedan logo
 
 
 
spacer
home > ebr > spring 2008 > mass spectrometry for the next generation
PUBLICATIONS
European Biopharmaceutical Review

Mass Spectrometry for the Next Generation

High performance mass spectrometry advances provide powerful new research capabilities with sophisticated software solutions to biopharmaceuticals. Michael Willett of Bruker Corporation informs us of the latest developments in this cutting-edge technology

In the past year, major new developments in cutting-edge, highend mass spectrometers and mass spectrometry-based software solutions have reached research scientists in the pharmaceutical and biotechnology industries, positively impacting their research. A new generation of proteomics data warehousing, proteomics data mining and proteomics project management software is now in use by research scientists, especially in Europe. Secondly, new tools for biologics drug development have become available. In addition, mass spectrometry-based metabolic profiling is now combining complementary methods of metabolite quantitation and structure determination by nuclear magnetic resonance (NMR) with exact mass analysis by electrospray mass spectrometry (ESI-MS). Furthermore, new generations of highend mass spectrometers have now become particularly useful to pharma and biotech researchers dedicated to drug discovery and development, especially when coupled with the latest advanced solutions in MALDI molecular imaging of human and research model tissues, along with software solutions for biomarker panel discovery, identification and validation, for example.

NEW PROTEOMICS DATA WAREHOUSING AND PROJECT MANAGEMENT SOFTWARE PRODUCE POSITIVE PROTEIN RESEARCH RESULTS

With a new generation of proteomics data warehousing software now in use, next-generation bioinformatics platforms addressing scientists’ current needs in proteomics identification and biomarker profiling, quantification and validation have become available. As a comprehensive solution for qualitative and quantitative liquid chromatography (LC)-MS/MS protein analysis, such proteomics software can now support all current label chemistries including multiplexed labels, as well as label-free quantification. Interactive validation of protein quantification based on raw LC/MS data has become simple and straightforward, streamlining the discovery process through decoy auto-validation algorithms and algorithms that produce non-redundant protein result lists across entire proteomics projects, including brain proteomics projects.


Read full article from PDF >>

Rate this article You must be a member of the site to make a vote.  
Average rating:
0
     

There are no comments in regards to this article.

 You must be a member of the site to make a comment.
spacer
Michael Willett has been the Public relations and Investor Relations Officer of Bruker Corporation since September 2002, and was the Investor Relations Director at Bruker Daltonics from 2000 to 2002. Prior to joining Bruker Daltonics, Michael was the International Finance, Tax and Accounting Manager at a leading healthcare policy consulting firm from 1998 to 2000. Previously, he was IR Director at a computer company for five years. Early in his career, Michael was an Audit Manager with Ernst & Young LLP in New York, Barcelona and Zurich. A CPA, he holds a BA and a BSE from the University of Connecticut, and an MBA from Columbia University, followed by post-MBA study at Northwestern University in Chicago.
spacer
Michael Willett
spacer
spacer
Print this page
Send to a friend
Privacy statement
News and Press Releases

Glatt Selected for GMP Biorefinery Engineering Project by NSTDA in Thailand

Bangkok, Thailand and Weimar, Germany – September 2020: National Science and Technology Development Agency Thailand (NSTDA) is implementing the Government’s Thailand 4.0 initiative to promote strategic biotechnology growth at the country’s Eastern Economic Corridor of Innovation (EECi). One part of this new BIOPOLIS complex is the GMP Biorefinery Pilot Plant at EECi, for which German engineering company Glatt Ingenieurtechnik was selected to provide the engineering services. The contract between NSTDA and Glatt comprises the Conceptual and Basic Design phases for the GMP Biorefinery.
More info >>

White Papers

New Temperature Profiles from a Global Study

Laminar Medica

Recently there has been an influx of temperature mapping studies to collect sufficient ambient data to develop temperature profiles.  Solid temperature profiles on specific shipping routes are required to ensure streamlined packaging and robust lane qualification. The most reliable method to develop temperature profiles is to capture the actual reading from shipments, as well as using the historical and meteorological data to increase the confidence level.
More info >>

 
Industry Events

12th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology

8-11 February 2021, Vienna, Austria

In continuation of the very successful scientific meetings in Budapest, Paris, Berlin, Florence, Geneva, Barcelona, Malta, Istanbul, Lisbon, Glasgow and Granada, the 12th PBP World will be held in Vienna from 8-11 Feb 2021. This every two year held conference has gained an ever increasing impact among the pharmaceutical scientists: With up to 1000 submitted abstracts and about 1300 participants it has become a well-established major meeting, attracting scientists from all over the world.
More info >>

 

 

©2000-2011 Samedan Ltd.
Add to favourites

Print this page

Send to a friend
Privacy statement