spacer
home > ebr > summer 2008 > dealing with the deluge
PUBLICATIONS
European Biopharmaceutical Review

Dealing with the Deluge

Flow cytometry is a technique for cell characterisation that is popularly used in basic and translational research for understanding, for example, how mutated stem cells may confer therapy resistance to a tumour (1). Alternatively, cell characterisation can be used to measure cell receptors during activation or as a response to immunosuppressive drugs. A flow cytometer consists of a narrow, hydrodynamically-focused stream of cells that pass and are interrogated by a light source. The cellsí physical characteristics of size and granularity, as well as any fluorescent labels attached in or on the cells, scatter the beam of light. Fluorescent labels attached will then be excited, enabling the appropriate emission characteristics to be measured in relative terms of fluorescent intensity.

Flow cytometer manufacturers have responded to the needs of modern researchers by developing faster systems that can measure more variables over shorter time periods for applications such as detecting tumour cells in peripheral blood and examining different aspects of stem cell differentiation. However, the ability of the software that flow cytometers rely on to analyse and visualise the rapidly rising tide of data now being generated has lagged way behind these improvements in instrument technology. This article examines some of the approaches that enlightened software manufacturers are now taking to speed up and simplify data analysis and support the revolution in flow cytometry research.


Read full article from PDF >>

Rate this article You must be a member of the site to make a vote.  
Average rating:
0
     

There are no comments in regards to this article.

spacer
Gillian Byrne is the Product Specialist of Applied Cytometry. Gillianís responsibilities include establishing and maintaining expert technical knowledge of the companyís products and determining the market needs for effective product launch strategies. She plays an active role in developing business relationships with customers of the flow cytometry industry as well as displaying her expert product knowledge at global industry related events. As a biomedical science graduate, Gillianís career was mainly spent in the public sector before venturing into the private sector, working as a state registered biomedical scientist for a clinical microbiology laboratory. Here she gained valuable skills in all aspects of bacteriology, serology and molecular biology, giving her first hand experience of the biomedical industry.
spacer
Gillian Byrne
spacer
spacer
Print this page
Send to a friend
Privacy statement
News and Press Releases

Arquer Diagnostics Appoints Nadia Whittley as CEO


More info >>

White Papers

Exploring Protein Stability by nanoDSF

NanoTemper Technologies GmbH

nanoDSF determines thermal and chemical protein stability with ultra-high resolution and with unmatched reproducibility. The detection of the intrinsic tryptophan and tyrosin fluorescence enables measurements at close-to-native conditions in any buffer, even in the presence of detergents. nanoDSF is applied in antibody engineering, membrane protein research, formulation and quality control.
More info >>

 
Industry Events

CPhI India 2017

27-30 November 2017, Bombay Exhibition Centre & MMRDA Grounds, BKC

Connect, network and interact with 1,400+ exhibitors at India's largest and leading pharmaceutical event. CPhI and P-MEC India is the gateway for you to meet the movers and shakers in Indiaís pharma industry to source high quality pharma solutions at the most competitive prices. Register today for free via: gotocphi.com/india2017
More info >>

 

 

©2000-2011 Samedan Ltd.
Add to favourites

Print this page

Send to a friend
Privacy statement