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Pharmaceutical Manufacturing and Packing Sourcer

The Therapeutics of Injections

Kevin Maynard, Business Development Director at Imprint Pharmaceuticals Ltd, investigates the solublisation and recovery of injectable pharmaceutical materials, and the importance of usability and safety for end users

Many injectable drugs need to be reconstituted either at home or in the clinic. Special devices have been developed to improve the reproducibility, simplicity and safety of the reconstitution of these therapies for end users, including healthcare workers and patients.

Pharmaceutical companies are becoming ever more successful in bringing the fruits of the human genome project to market. Treatment of diseases such as cancer, rheumatoid arthritis, Crohnís disease and diabetes are being transformed by these therapies. However, many of the therapies require injection and, hence, come with all the complications, both technical and presentational, that injectable therapies bring.

Many of these therapies require frequent injections; depending on the nature of the disease and the patientís individual condition, those injections could be weekly, daily, or even more frequent.

Many injectable therapeutics are stored as powders; they are more stable in this form. Therapeutics stored as a powder need to be solublised with a liquid diluent and transferred to an injection device before being injected, resulting in an additional operation for untrained users to carry out. This step can be quite complex, with multiple variants in the reconstitution process depending on the therapy, the delivery device and the userís setting and knowledge. This creates significant issues for those unaware of the problem.


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Kevin Maynard is the Business Development Director of Imprint Pharmaceuticals Ltd, a company focused on providing solutions to the reconstitution and delivery of complex formulations. Over the last 10 years, Kevin has concentrated his efforts on providing clients with practical technology to solve some of the most intractable problems in managing complex fluids at the bedside or clinic. He has a PhD in Pharmacology and 20 yearsí experience in drug delivery, cancer biology and therapeutic formulations.
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Kevin Maynard
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