Cognitive Drug Research: the world’s leading provider of automated cognitive assessment services to the pharmaceutical industry.

• Pioneer in fully-automated cognitive testing
• Over 20 years of experience
• Extensive normative, patient and drug databases
• Flexible suite of platforms for any study design
• 24-hour service and support
• Scientific and system validation
• Seamless integration into clinical trials

In 1986, Professor Keith Wesnes introduced the little black response box, revolutionising the world of computerised cognitive assessments. CDR now employs 75 staff across three locations in Europe, North America and Australia. The CDR System has been specifically developed over the last 25 years to definitively assess enhancement and impairment of human cognitive function in clinical trial settings, and as a result CDR now has the largest normative clinical trial database in the world.

• CDR System used in over 1000 trials, including each of the top 15 global pharmaceutical companies and over 130 clients in total
• Experience in over 47 therapeutic categories.
• System is documented to ICH GCP and FDA 21CFR part 11 standards
• Cited in well over 250 publications and 448 conference abstracts
• Twice received the most prestigious business accolade in the UK, the Queen’s Awards for Enterprise

CDR provides a fully customised cognition assessment service, support and consultancy from protocol design to analysis—implementing assessments into any trial design to virtually any timeline.

• Pre-study assessment on appropriate measures and testing schedules
• Investigator training
• Preparation and delivery of The CDR System
• Query management of cognitive data
• Analysis, interpretation and reporting of study results

The CDR System has a core battery of tasks which assess the major aspects of cognitive function known to be influenced by medicines and disease. This core battery can be supplemented as required with a wide range of other tests which are either fully computerised or computer assisted. Responses are measured with true millisecond precision using the proprietary YES/NO response box. A typical comprehensive cognitive profile can be obtained with The CDR system in around 18 minutes. The CDR System can be administered in any clinical setting and to any clinical population and used throughout the drug development process, from first-to-man trials to large worldwide Phase III and IV trials. The core tests are fully automated and do not need to be administered by specialist staff. Participants do not use the keyboard and are trained on the tests prior to the start of the study. Data is recorded automatically and securely.

CDR Benefits:

• Help you reach a go/no go decision as a validated biomarker
• Improve your benefits vs competitor profile
• Support your due diligence activity and form part of your Risk Management Plan
• Aid your regulatory submissions – approved efficacy endpoint
• Provide Quality of Life evidence to support your submissions to Health Technology Appraisal boards and address subsidy/reimbursement issues in the market.

European Office:
Phone: +44 (0)1491 878700
Email: info@cdr.eu.com
www.cdr.eu.com

North American Office:
Phone: +1 312 640 0320
Email: info@cdr.us.com 
www.cdr.us.com