BioFocus offers a comprehensive suite of discovery products and services. These are available separately or as an integrated drug discovery solution, backed by a centralized project management system.  Our headquarters are in Saffron Walden (near Cambridge), UK, with facilities in the US and Switzerland, and sales offices in Japan, Singapore and the US. We employ 250 staff offering a range of products and services to biotech, pharma as well as patient and non-profit organizations. Our services include:

Integrated drug discovery: conducting gene-to-candidate discovery programs using multidisciplinary teams

Target discovery: identifying novel targets using human primary cells

Assay development and screening: compound screening using tailored biochemical and cellular assays

Natural products: hit finding and lead generation from 8,000 fungal and 15,000 actinomycete strains. 

Structural biology: revealing protein-drug interactions by X-ray crystallography

Fragment-based drug discovery: label-free binding, high concentration biochemical assay, protein/ligand crystallography and NMR technologies. 

In silico drug discovery: accelerating drug discovery using computational technologies

Medicinal chemistry: designing and synthesizing novel drug candidates

ADME/PK: performing comprehensive ADME and pharmacokinetics

Compound libraries: accessing synthetic and natural product compound libraries for high-throughput screening

Compound management: acquiring, managing, controlling quality and distributing client screening collections