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| home > ebr > Autumn 2010 |
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 PUBLICATIONS |
European Biopharmaceutical Review |
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| Trish Meek at Thermo Fisher Scientific and Dennis Fallen at Fisher BioServices discuss the importance of informatics tools in the translational science process, highlighting laboratory information management systems as an ideal solution for more effective collaboration. |
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| Translational medicine is a new term for an old approach that has again become relevant to contemporary issues. However, its true value lies in the seamless integration of the public and commercial sector, explains Bob Damms and Ian Rhodes at PA Consulting Group. |
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| As the opportunities for conducting trials in developing countries increases, Gary Muddyman at Conversis weighs up the risks and challenges involved in working in these countries given their unique cultures and little understanding of Western medical concepts. |
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| David Koos, Steven F Josephs and Ewa Carrier at Entest BioMedical, and Thomas E Ichim at Medistem Inc, look at the approaches being used to target the main cause of cancer: the tumour stem cell. |
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| Reporting on the recent developments of anti-tumour immune response studies, Karl-Hermann Schlingensiepen at Antisense Pharma GmbH presents potential treatments emerging from a combination of traditional approaches. |
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| Within the opening decade of the 21st century, biological products as therapeutics have taken their place in the ranks of the top 10 global pharmaceutical drugs. Consultant Emile Bellott looks at the impact this market growth has had worldwide. |
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| The ability of RNA interference – the pathway through which protein synthesis can be blocked – to silence disease-causing genes effectively has placed it as one of the most promising technologies driving the future of the pharmaceutical market. Balasubramanyam Nistla at GBI Research looks at the technology’s potential in cancer care. |
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| Manfred Gossen at BCRT, Berlin describes how Tet technology can facilitate the translation of scientific advancement into medical progress, giving examples in diabetes and cancer, and its vast innovative potential in advancing pharmacological and biomedical research. |
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| Gregory V Goldmacher at ICON Medical Imaging makes the case for a centralised approach versus local readers when determining a subject’s suitability for a clinical trial, citing robust statistical results and cost savings as key benefits of using this method. |
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| In contrast to the ‘one drug, one target’ model, recent approaches to reprofiling have revealed that many drugs act on more than one target. Daniel Auerbach, Lukas Baumann and Mandana Rezwan at Dualsystems Biotech look at the variety of technologies available for target identification and how this can be used to reposition marketed drugs to alternative indications. |
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| Adaptive trial designs are the most cost-effective, efficient way to get the best out of a clinical trial endeavour, argues Shein-Chung Chow at Duke University School of Medicine, in his review of the range of different options available to today’s trial organisers. |
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| As always, speed is of the essence in drug discovery, and methodologies that streamline the research process are very welcome. Ulf Landegren at Uppsala University shows how biomarker technologies are up to the challenge. |
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| As the marketplace becomes more competitive, the technological demands of the research process can often become too great for individual CROs. Samantha James of Simbec Research introduces the idea of centralised laboratory services, which can offer the specialist skills required for the task. |
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| While regulatory authorities are introducing guidelines to take biopharma through the 21st century, Hedley Rees at Biotech PharmaFlow argues that the problem of modernisation stems not from regulations, but from the management culture within the industry. |
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| The integrity of data quality is fundamental to any research project; Diane Meakin and Janette Waterhouse at R5 Pharmaceuticals provide ways in which confidence in data can be controlled and improved. |
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| Chris Ullman of Isogenica Ltd gives a detailed analysis of how phage display methods can assist the discovery process in a variety of ways, especially when it comes to finding new molecules for protein and peptide-based therapeutics. |
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| As pharmaceutical investment in the Kingdom of Saudi Arabia continues to grow, Rani Abraham at ClinTec International details the challenges, regulations and cultural aspects that need to be considered. |
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Although still in its early growth phase, Satya Dash at the Association of Biotechnology Led Enterprises explains why the future of India’s presence in the global biotechnology market is dependent on the political landscape and government support. |
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News and Press Releases |
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UK Tech Spinout Salient Bio Launches Fastest Ever Robotic COVID-19 PCR-Based Tests With A Gold Standard Accuracy Of Over 99%
Rapid test platform is up to three times faster than competitors for mass testing and is already being used by a range of businesses that require regular human contact in sectors including logistics, entertainment, sports, healthcare and education.
Strategic aim is to provide affordable, effective and easy-to-access pre-emptive diagnostic solutions for a range of medical conditions that facilitate early intervention and improve overall health outcomes.
More info >> |
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White Papers |
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Time lapse photography to demonstrate the potential antimicrobial abilities of Dycem contamination control flooring
Dycem
A defined volume of bioluminescent reporter bacteria was deposited onto 20 mm x 20 mm coupons of Dycem flooring, vinyl tile and ITW Alma tacky mat. Through monitoring of bacterial bioluminescence, metabolic inhibition was observed on all three surfaces however the effect occurred more rapidly on Dycem flooring than on vinyl or ITW Alma. Recovery counts after three hours of exposure to the floor surfaces showed between a 65% and 100% decrease in the number of viable organisms recovered from Dycem flooring compared to controls. On vinyl and ITW Alma flooring, there were slight increases in the number of viable survivors recovered compared to controls. Dycem flooring inhibited the metabolic activity and reduced the number of viable survivors recovered of Salmonella enterica Serovar Typhimurium DT104 pGLITE. It remains unclear as to whether this effect is attributable to the impregnated biocide or rapid drying of the inoculum on this surface.
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Industry Events |
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12th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology
8-11 February 2021, Vienna, Austria
In continuation of the very successful scientific meetings in Budapest, Paris, Berlin, Florence, Geneva, Barcelona, Malta, Istanbul, Lisbon, Glasgow and Granada, the 12th PBP World will be held in Vienna from 8-11 Feb 2021. This every two year held conference has gained an ever increasing impact among the pharmaceutical scientists: With up to 1000 submitted abstracts and about 1300 participants it has become a well-established major meeting, attracting scientists from all over the world.
More info >> |
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