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European Biopharmaceutical Review

ebr
Summer 2013

   
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STRATEGY AND FINANCE
New Finance Models

A Common Cause

Oliver Timmis at the AKU Society investigates how collaboration between medical research charities and patient organisations could fund vital studies.
 
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Science and Innovation
Phage Prevention

Detection Validation

The presence of bacteriophages in fermentation and the facility environment needs to be constantly monitored by microbiologists. But when this is not possible, what other options are there? Marcin Los at Phage Consultants sheds light on this growing problem.
 
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Rediscovery

More for Less

The advantages of drug repurposing are vast, however the development costs involved risk stifling this innovation, argues Bruce Bloom at Cures Within Reach.
 
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Regulation and Finance

Tailored Medicine

With the help of a revised European Directive, bespoke treatments are entering the oncology industry and are being presented as safer and more effective, as Vincent O’Neill and Debasish Roychowdhury at Sanofi Oncology demonstrate.
 
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Organism Development

All Systems Go

A new discipline has risen in recent years: systems biology. José Manuel Mas and Albert Pujol Torras at Anaxomics describe the two main strategies that are used in this scheme – the topological and the functional.
 
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BioResearch and Innovation
Genotoxicity Screening

Early Identification

Steve Beasley at Gentronix assesses the need for the early screening of genetic toxicity to minimise late-stage attrition costs and improve compound quality.
 
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BioDiscovery
Drug Development

Tunable Half-Life Technology

Mark Perkins at Novozymes Biopharma analyses the challenges of biological drugs’ short half-lives, and how extension technology could resolve this problem.
 
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Drug Discovery
Tailoring Treatments

Critical Overhaul

Rick Morrison at Comprehend Systems demonstrates how the combination of rising patient demands and pioneering new technology could be the solution to bespoke medicine.
 
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Repurposing

Intelligent Approaches

In order to develop the drug discovery market and find indications for orphan conditions, alternative methods have to be implemented.Robert Scoffin and Alan Rothaul at Re-Pharm investigate the potential of drug repurposing or reprofiling to address this issue.
 
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Anti-Infective Drugs

The PK/PD Complex

In revealing the specific distinctions of a compound, pharmacokinetic and pharmacodynamic properties are being used and are becoming an increasing area of interest, suggests medical author Deborah Erickson.
 
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Cancer Therapy

The T Cell Promise

The evolution of the cancer therapy field is progressing through the help of T cells, which may eventually prove able to eradicate tumours. Namir J Hassan and Joanne Oates at Immunocore discuss the potential of this strategy.
 
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BioRegional
Bioregional

Innovative India

Andrew Barrett at Cambridge Consultants illustrates how Indian pharmaceutical companies are planning to create super-generics, and how they could potentially become a major force in the connected health market.
 
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INTERVIEW
Industry Interview

Insider Information

Jon Weisberg of SAFE-BioPharma reveals his career motivation and looks forward to the future of the biopharma sector.
 
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RESEARCH AND DEVELOPMENT
Oncology Drugs

Purposeful Reprofiling

A burgeoning trend in cancer prevention has been the treatment of patients with drugs that have already been approved in therapeutic areas other than oncology, as Rachel Meighan-Mantha at Citeline explains.


 
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Vaccines

Prevention is Better than Cure

Emanuela Signori at CNR-IFT and Vito Michele Fazio at UCBM discuss how recent research into the immune system biology has led to new strategies within the DNA vaccination area.

 
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Gene Therapy

Great Promise

Introducing therapeutic genetic material into a disease cell to correct phentotypes is becoming a popular concept in curing monogenic conditions. Bobby Gaspar and Christine Rivat at UCL talk us through this model.
 
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Protein Drugs

The Sugar is the Key

Taegen Clary at Agilent explains how analytical methods can aid the manufacturing process of protein biologics, which are especially important at a time of increasing patent expirations.
 
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Detection Techniques

Identifying Impurities

Process-related contamination from host cells is a relentless problem that needs to be addressed. Andrew Kenyon at RSSL assesses the situation and suggests alternative methods to tackle this issue.
 
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Edited by
Dr Deborah O'Neil,
Chief Executive and Scientific Officer,
NovaBiotics Ltd
Published quarterly in
January, April,
July and October

News and Press Releases

RWS Life Sciences Welcomes New VP of Quality

RWS Life Sciences welcomes Clarice Streets, ASQ, CMQ, OE, as Vice President, Global Quality and Process, in charge of the strategic direction and implementation of its Quality system, underlying organizational processes, and change management.
More info >>

White Papers

Nanoparticle Tracking Analysis. A Review of Applications and Usage in the Analysis of Exosomes and Microvesicles

NanoSight

The study of exosomes and other cell-derived microvesicles is an area of rapidly growing importance and the subject of intense interest and research. The previous lack of suitable methods for their detection, analysis, enumeration and phenotyping is proving to be a significant limitation in these studies. This mini-review shows the degree to which the technique of Nanoparticle Tracking Analysis (NTA) is helping to address these problems.
More info >>

Industry Events

SMI Immuno-Oncology Conference

25-27 September 2018, Copthorne Tara Hotel, London, UK

Immuno-Oncology is a fast-paced field with massive potential to deliver successful and durable cancer therapies, and SMi's Immuno-Oncology Conference will focus on a few key areas of the field with a representation of the whole industry under each area. These areas will be drawn together to look towards the future of Immuno-oncology and how the field can progress.
More info >>

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