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European Biopharmaceutical Review

ebr
Winter 2014

   
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Editor’s Letter

Deborah O’Neil reviews how regulations can assist with safer therapies, and explores some of this issue’s focus features.
 
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Science and Innovation
Monitoring Aggregation

Characterisation Techniques


Therapeutic protein molecules are prone to degradation in the body if their binding efficacy is lost, but Pauline Carnell and Sarah Newell at NanoSight Ltd suggest that a new technique may provide the solution.
 
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BioBusiness Development
Strategy and Finance

Rising Up: Part 2


In the second of a two-part series, Graham Scholefield and Markus Thunecke at Catenion explore new strategies to integrate payer needs with R&D decision-making.
 
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BioResearch and Innovation
Antimicrobial Therapeutics

First Class


Vanessa Duncan, Douglas Fraser-Pitt and Derry Mercer at NovaBiotics Ltd review how peptide anti-infectives are offering a different approach to the therapeutic field.
 
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Discovery Technology
NMR-Based Methods

Data Streaming


A new tool for optimising cell feed strategy and upstream process development has been unveiled. Nuclear magnetic resonance technology is successfully improving Quality by Design data, says Frederic Girard at Spinnovation Biologics.
 
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Drug Discovery
Phenotypic Drug Discovery

Target Practice


Target deconvolution using phenotypic screening methods is beginning to provide greater opportunities for the development pipeline. Jim Freeth at Retrogenix explains how this could help to produce many new and innovative drugs.
 
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Drug Discovery

Data Mine


Pooja Jain at PharmaPendium reports on how the amount of data generated by the industry is outweighing the information management strategies that are already in place.
 
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CANCER FOCUS
Oncology Approvals

Cancer Concerns


Vijaya Vulapalli
at GBI Research discusses the many challenges that the oncology sector faces. Inaccessible treatments, high costs and increasing death rates are just a few of the obstacles that need to be tackled.
 
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Cancer Diagnostics

Making a Mark


Alfred Hansel and Martina Schmitz at oncgnostics GmbH explore how DNA methylation-based epigenetic markers are demonstrating their vast diagnostic potential for in vitro testing.
 
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APPLIED RESEARCH, DEVELOPMENT AND PRODUCTION
Bioprocess Monitoring

Real-Time Approach


The complexity of using living cells as production systems represents a major challenge in bioprocess design and control. Markus Luchner, Timo Schmidberger and Gerald Striedner at ACIB highlight how proton transfer reaction mass spectrometers hold the potential to change this.
 
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REGIONAL UPDATES
Bioregional

Investing in the Future


Uldouz Berenjforoush at Frost & Sullivan examines why Azerbaijan is becoming an attractive destination for new investors, as their expanding economy and plans to develop primary care come to the forefront.
 
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INTERVIEW
Industry Interview

Business Speak


Dr Jean-Pierre Wery, President of Crown Bioscience, speaks to EBR to discuss his business philosophy, share his goals for the coming year, and reveal the secret of his success.
 
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DEVELOPMENT AND PRODUCTION
Molecular Treatments

mRNA: Get the Message


Ingmar Hoerr at CureVac reveals how messenger ribonucleic acids are beginning to transform modern molecular medicine as a novel therapeutic class.
 
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MARKETPLACE
Proof of Concept

Adding Value


Pinar Akpinar, Cyril Clarke and Nigel Gregson illustrate how proof-of-concept and proof-of-value are linked when bringing a new drug to market.
 
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In Brief

Return of the Blockbuster?


Against the popular consensus of industry leaders, Emile Bellott considers whether the emphasis on niche indications is over as the blockbuster era makes a comeback.
 
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BIO-SECURITY
Bio-Security

Pipeline of Terror


Boaz Ganor, Miri Halpern Wernli and Mollie Shields Uehling at Actelion debate the threat of terrorism to the biopharmaceutical industry. What can the industry do to protect itself?
 
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BIOIMAGING
Four-Dimensional Imaging

A Deadly Bite


Dr Bülent Peker at Olympus Europa demonstrates how four-dimensional imaging could tackle the complex blood stage of the malarial pathogen Plasmodium falciparum.
 
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Image Processing Techniques

Marked Data


More sophisticated image analysis techniques would allow for greater optimisation of biomarker data. Andrew J Buckler and James C Keith at Elucid Bioimaging Inc explain the advantages that this could bring.


 
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Edited by
Dr Deborah O'Neil,
Chief Executive and Scientific Officer,
NovaBiotics Ltd
Published quarterly in
January, April,
July and October

News and Press Releases

Horizon Discovery and Fulcrum Therapeutics Form Collaboration for Novel CRISPR-Based Target Discovery in Genetic Diseases

The collaboration will utilize Horizon’s world-leading CRISPR-based screening platform to identify novel targets for regulating gene expression.
More info >>

White Papers

ConsulTech GmbH

ConsulTech GmbH

ConsulTech is a consulting company founded in 1992. Since then, we have been supporting biotech-nology, pharmaceutical and medical technology companies as well as research institutions with the entire process of setting-up and executing proposals for R&D projects. In projects funded by the European Commission, ConsulTech supports the coordinator by resuming administrative tasks allow-ing coordinators and partners to fully concentrate on the scientific and technical success of the pro-ject. We solve financial and administrative issues, organise meetings, take care of the timely delivery of milestones and reports and much more.
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Industry Events

7th annual Orphan Drugs and Rare Diseases UK

18-19 October 2017, Holiday Inn Kensington Forum, London

SMi Group is thrilled to present the 7th annual Orphan Drugs and Rare Diseases conference, taking place on 18th & 19th October 2017 in Central London, UK. This year’s theme will be focused towards discussing strategies for patient engagement, market access and gene therapies to enhance rare diseases and orphan drug research.
More info >>

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