spacer
home > ebr > Autumn 2014
PUBLICATIONS

European Biopharmaceutical Review

ebr
Autumn 2014

   
Text
PDF
Editor’s Letter

Deborah O’Neil ponders the recent Ebola outbreak and discusses some of this edition’s focus features.
 
view
download pdf
Science and Innovation
Mass Spectrometry

Molecular Weight


Intact mass analysis has the benefits of minimal sample preparation, high-speed analysis and minor method-induced modifications. Nicholas Michael and Pat Easton at Reading Scientific Services Ltd explain.
 
view
download pdf
Column Technology

HPLC’s Golden Jubilee: Part 2


In the second of a two-part series, Ronald Majors from Agilent Technologies reviews the progress of highperformance liquid chromatography over the last 50 years and considers what the future holds.
 
view
download pdf
bullet
BioResearch and Innovation
Nanotechnology

On Target


A sound understanding of biological responses, combined with close coordination of drug delivery mechanisms and particle toxicology, are essential for the safe and effective use of nanoparticles in drug delivery, advises Aiswariya Chidambaram at Frost & Sullivan.
 
view
download pdf
BioDevelopment
Transient Gene Expression

Shifting the Balance

Stable cell line generation can be costly in terms of time, labour and money. Karen Donato, Krista Steger and Meg Duskin at MaxCyte, Inc weigh up transient gene expression as an alternative.
 
view
download pdf
Q&A: Cell Line Development

Path to Progress


FUJIFILM Diosynth Biotechnologies’ Alison Porter tells EBR what must be considered when creating a new host cell line, and gives tips on how to save future development time and meet production requirements.



 
view
download pdf
Mammalian Cell Culture

Testing Times


Universitat Autňnoma de Barcelona’s Francesc Gňdia recommends the design of experiments approach as a means to accelerate the screening of effi cient compounds and the corresponding optimal conditions.
 
view
download pdf
bullet
Legal, Regulatory and Public Policy
Regulatory Challenge

Rapid response


The growing advances in genomics and how this area fi ts in with personalised medicine is uncharted territory, particularly for regulatory agencies. Regina Au at BioMarketing Insight contemplates the current approval processes.


 
view
download pdf
Personalised Medicine

Individual Focus

With molecular profi ling allowing for patient-specific therapeutic strategies, the need to encourage research must be balanced against demands for privacy protection, reports Emma Naks at EBR.
 
view
download pdf
EU Legislation

In Harmony?


Shuna Mason from CMS points out that although recent legislative changes reveal an intention to promote personalised medicine within the EU, there is still some way to go in harmonising regulation.
 
view
download pdf
bullet
BioDevelopment and Regulatory
Temperature Standardisation

Playing it Cool


Rolf Ehrhardt and Maria Thompson from BioCision raise awareness of the importance of temperature standardisation in the field of cell biology, and evaluate current practice.
 
view
download pdf
bullet
INTERVIEW
Industry Insight

Hot Spot


EBR talks to Frédéric Druck at BioWin about Wallonia, Belgium, and why this region is proving a favourite for companies looking to focus on immunology R&D.
 
view
download pdf
bullet
INDUSTRY DYNAMICS
In Brief

A Tale of Two Cities


Despite their common heritage, the US and UK have evolved two distinct approaches to the provision of healthcare and managing costs on a national scale. Emile Bellot explores further.
 
view
download pdf
bullet
BUSINESS STRATEGY
Industry Collaboration

Better Together


Pharma companies must realise that productivity does not exist only in delivering effective new compounds, but also in playing a responsive and active part alongside others, reason Peter Wagner and Christoph Schnorr of Quintiles.


 
view
download pdf
Open Innovation

Compound Interest


Simon MacKenzie and Sylviane Boucharens at BioAscent Discovery Ltd suggest why using corporate compound collections as a shareable asset is both promising and valuable.
 
view
download pdf
Clinical Supply Partnerships

Need for Speed

Martin Lamb and Claudia Williams at Biotec Services International propose partnering with a clinical supply business to help cut costs and reduce time to market.
 
view
download pdf
bullet
BIOIMAGING
Drug Development

Eye for Success


MPI Research’s Scott Haller believes that contemporary molecular imaging offers pharma a set of tools capable of dramatically de-risking clinical drug development.
 
view
download pdf
Kinetic Modelling

Made to Measure


When it comes to oncology imaging, volumes can allow for a more complete picture, as well as a sophisticated estimation of tumour growth. David Raunig, Gregory Goldmacher and Stephanie Owens at ICON reflect.
 
view
download pdf
   
spacer
Edited by
Dr Deborah O'Neil,
Chief Executive and Scientific Officer,
NovaBiotics Ltd
Published quarterly in
January, April,
July and October

News and Press Releases

POP TEST ADDRESSES THE PROBLEM OF UNRELIABLE DATA FROM CONTINUOUS GLUCOSE MONITORS

A major insight relating to the unreliability of data from continuous glucose monitors was published in the Nature journal, “Scientific Reports”, by Neil Theise, MD., the Lead Scientist of Pop Test, LLC and colleagues. The discovery of the “Interstitium”, a newfound human organ, by Dr. Theise and his collaborators, can be viewed by using the link https://www.nature.com/articles/s41598-018-23062-6 Continual glucose monitoring via an indwelling cutaneous needle measuring glucose in interstitial fluid (now identified to be in the “interstitium”) has been a game changer in the treatment of type 1 diabetes mellitus because of its accuracy. However, the needles used to collect this glucose containing fluid often fail in as little as a week. Despite the reliance on fluid from this space, the microanatomy of the interstitium has never been defined. The sensors currently in use were developed with the presumption of interstitial fluid being located somewhere in the sub-epidermal layers of the skin, but the actual anatomy relating to needle placement was always unclear.
More info >>

White Papers

8 Ways To Reduce Tablet Manufacturing Costs

Natoli Engineering Company, Inc.

It’s no surprise that in today’s economy, companies are facing budget cuts across the board. In an effort to address these challenges, this list of 8 Ways to Reduce Tablet Manufacturing Costs was compiled.
More info >>

Industry Events

Automatica 2018

18 June 2018, Messe München, Munich, Germany

Automatica is the leading exhibition for smart automation and robotics. It features the world's largest range of robotics, assembly systems, machine vision systems and components. For more information go to automatic-munich.com/visitors
More info >>

©2000-2011 Samedan Ltd.
Add to favourites

Print this page

Send to a friend
Privacy statement