spacer
home > ebr > Autumn 2018
PUBLICATIONS

European Biopharmaceutical Review

ebr
Autumn 2018

   
Text
PDF
Editor’s Letter

EBR's Editor, Dr Deborah O'Neil, details all the innovations touched upon in this issue and how the majority can enhance cancer treatment.
 
view
download pdf
bullet
peptides and proteins
Label-Free Biosensing

Protein Progression

Following a significant increase in quality, peptide and protein microarrays now have the potential to offer brand new opportunities in pharmaceutical and proteomics R&D, claims Güenther Proll at Biametrics.
 
view
download pdf
Process-Specific Versus Generic Host Cell Protein Impurity Assays

Biologics Process Analysis

Given the rise in therapeutic antibody production, it has become more important than ever to address issues associated with host cell proteins, as detailed by Ken Hoffman, Eric Bishop, Dr Alla Zilberman, and Dr Jared Isaac at Cygnus Technologies.
 
view
download pdf
Generating High-Quality Protein Reagents from Eukaryotic Cells

Cell Culture Considerations

Both Escherichia coli and eukaryotic systems have their pros and cons, yet the former is selected more often due to speed and cost implications. Dr Mark Abbott at Peak Proteins discusses the factors to be considered.


 
view
download pdf
Improving Pharmacokinetic Assays in a Regulatory Bioanalysis Setting

Applying Affimers

Dr Amanda Nicholl at Avacta Life Sciences expresses the fundamentality of pharmacokinetic assay results in the phases of drug development and how to increase the effectiveness and efficacy of antibody drug development.
 
view
download pdf
Peptides in Plasma

Determining Peptides

Determination in plasma can be particularly complicated, especially when dealing with peptides, but Professor Hermann Mascher at pharm-analyt believes it is still a route worth taking.
 
view
download pdf
bullet
Formulation and Quality Control
Purifying Oligonucleotides

Produce Potential

Dr Cecilia Unoson and Dr Lars Haneskog at Bio-Works Technologies delve into whether the necessary yield and purity of oligonucleotides can be attained through anion exchange chromatography.
 
view
download pdf
bullet
Innovations in Oncology
Advanced Therapies

Rising to the Challenge

Dr Fiona Thistlethwaite at The Christie Hospital and Dr Ian Thomas at Aptus Clinical explore the challenges of bringing advanced therapy medicinal products to market and the considerations that must be made.
 
view
download pdf
Tissue-Agnostic Approvals

A New Oncology Era

New advances in tumourigenesis have laid the foundations for a molecular marker that assists in defining and treating cancers, explains Dr Terese Johansson at NDA Group.
 
view
download pdf
Cancer Therapy Innovations

Oncological Advances

Dr Kathryn D Bungartz at N-of-One provides an overview of how advanced imaging techniques and improved preventative measures have transformed the world of cancer innovation.
 
view
download pdf
In Vitro Bioassays

Candidate Selection

The cancer immunotherapies field has made notable progress in its clinical application, and combination therapies may be a viable force to drive these advancements further, suggest Thibault Janss and Sofie Pattijn at ImmunXperts.
 
view
download pdf
Diafiltration of Antibody-Drug Conjugates

Novel TFF Capsule Evaluation

The teams at Sanofi and Merck Group demonstrate the advantages of antibody-drug conjugates as cancer chemotherapeutics.
 
view
download pdf
bullet
Bioelectronics
Electroceutical Therapy for Chronic Pain

Effective Electroceuticals

Dr Sree Koneru at BioElectronic Corporation and Dr Kenneth McLeod at the State University of New York in Binghamton, outline the benefits of electroceutical treatments for many neurological disorders and compare this to the widely recognised central sensitisation.
 
view
download pdf
Benefits of Bioelectronic Medicine

Theory to Game Changer

As the use of bioelectronics is on the rise following the adoption of electric devices as main treatment options, Pascaline Vancraeyenest at Healtech identifies how the reliance on drugs is potentially becoming limited.
 
view
download pdf
The Future of Bioelectronic Medicine

Targeted Technology

Dr Deepak B Thimiri Govinda Raj, Prasanna Subramaniam, Dr Sri Saran Venkatachalam, and Dr Dinh-Toi Chu at Envirotransgene Biosolutions examine why bioelectronic medicine is regarded as a disruptive technology in healthcare.
 
view
download pdf
bullet
biopharmaceutical technology
In Brief

GOAL!

Following this year's approval of the first RNA interference-based human therapy, EBR's Industry Advisor, Emile Bellott, takes a look at its new role as a game-changer within the biopharma industry.
 
view
download pdf
   
spacer
Edited by
Dr Deborah O'Neil,
Chief Executive and Scientific Officer,
NovaBiotics Ltd
Published quarterly in
January, April,
July, and October

News and Press Releases

Envigo launches PATHWAY an optimized safety assessment solution to enable first in human clinical trials

11 March 2019, East Millstone, N.J. – Envigo, a leading provider of non-clinical contract research services and research models, announced today the launch of PATHWAY – an integrated solution that optimizes non-clinical safety assessment programs to enable first-in-human clinical trials. PATHWAY is designed to manage the complexity of the entire safety assessment process on behalf of the company’s pharmaceutical and biotechnology customers by integrating safety assessment study types and bioanalytical support with scientific and regulatory consulting, program design and project management.
More info >>

White Papers

Investigator Portals: Facilitating and Streamlining Communication & Collaboration with Study Sites

ArisGlobal

ArisGlobal LLC Investigator site personnel are often frustrated with the lack of transparency and communication with their sponsors, leading to significant dissatisfaction and withdrawal from current and future studies. The adoption of investigator portals gives sponsors a platform that fosters collaboration and improves site management. Learn about five key areas of sponsor-investigator site interactions deserving of electronic communication and collaboration. Technology and design aspects are also covered.
More info >>

Industry Events

ChinaBio® Partnering Forum 2019

8-9 May 2019, Shanghai, China

Access a world of opportunities through life science partnering in China. ChinaBio® Partnering Forum is the premier life science partnering event in China. The conference will be held May 8–9 in Shanghai, attracting biotech and pharma leaders from around the world along with hundreds of China-based developers of novel technologies for two days of productive partnering.
More info >>

©2000-2011 Samedan Ltd.
Add to favourites

Print this page

Send to a friend
Privacy statement