spacer
home > ebr > Summer 2021
PUBLICATIONS

European Biopharmaceutical Review

ebr
Summer 2021

   
Text
PDF
bullet
Biomarkers
Spearheading the Fight Against Infectious Diseases and Emerging Outbreaks

Anup Madan, Tina Green, Palanikumar Manoharan, and Abigail Cross at PPD

High throughput molecular technologies combined with bioinformatics are helping public health and diagnostic laboratories across the globe to monitor rising trends in drug resistance, detect emerging outbreaks faster, and stop outbreaks more effectively.
 
view
download pdf
Reconsidering the Future of Precision Medicine

Jonathan Lawson at Owlstone Medical

The study of the metabolome provides a comprehensive and current snapshot of what’s happening in the body, and offers a host of advantages in applications such as asthma, COPD, gut health, and cancer.
 
view
download pdf
Innovation in Oncology Clinical Trials

Brian Huber at ICON

Advances in genomics have ushered in a new era of precision medicine and the discovery that cancer cells can harbour specific genetic lesions, encouraging the emergence of therapies that selectivity target these lesions.
 
view
download pdf
The Power of Our DNA – Paving the Way for Precision Cancer Care

Isabelle Ray-Coquard at Centre Leon Bérard, Claude Bernard University Lyon I

By enhancing our understanding of tumour development and the biological processes responsible, optimal disease management and treatment strategies that are based on a patient’s precise genetic profile can be successfully formulated.
 
view
download pdf
bullet
Immuno-oncology
Are We Nearly There Yet? The Ongoing Journey of CAR T Cell Therapies

Sophie Lutter at OXGENE

Allogeneic T cell therapies are set to be game changers, improving the accessibility of CAR T cell therapies in terms of reduced cost of goods, manufacturing scalability, and improving patient eligibility.
 
view
download pdf
Accelerating OV Immunotherapeutic Innovation to Market

Kai Lipinski at Vibalogics

The combination of oncolytic viruses with immune checkpoint inhibitors and other therapies have the potential to transform the field of immuno-oncology and the way we approach cancer treatment.
 
view
download pdf
Alternative Therapies to Reverse Resistance to Checkpoint Inhibitors

Marisol Quintero at Hightlight Therapeutics

Identifying therapeutic approaches that enable the body’s immune system to recognise and kill tumour cells could be the key to extending the benefits of immunotherapy beyond use as a single line of treatment.
 
view
download pdf
bullet
Monoclonal Antibodies
The Vital Role of Transient Antibody Expression During Pandemics

Michael Fiebig at Absolute Antibody

Despite recent advances in large-scale transient expression, barriers must be overcome before it can be used to help produce the diagnostics, therapeutics, and vaccines needed during a pandemic.
 
view
download pdf
Streamlining Affinity Analysis for Accelerated Lead Screening, Characterisation, Optimisation, and Final Selection

Sartorius details its Octet® BLI systems, which offer a fluidics-free approach for the kinetic characterisation of binding interactions.
 
view
download pdf
bullet
In Vivo and Ex Vivo Gene Editing
The New Renaissance in Functional Genomics Screening

Benjamin Borgo at Merck

The functional genomics revolution has been led by the advancement of genome editing-based screening tools. This expanding technology offers endless possibilities, and has the potential to reveal the underlying biological networks for just about any phenotype.
 
view
download pdf
CRISPR: The Jump From Bench to Clinic

Cosimo Ducani at Moligo Technologies

A number of barriers stand in the way of CRISPR becoming a real possibility for patients. To address these problems, biopharma must consider how large quantities of DNA can be safely produced and distributed for scaled-up treatments.
 
view
download pdf
bullet
Discovery Technology
New Applications of Picodroplet Technology for Drug Discovery and Development

Olivia Hughes at Sphere Fluidics

High throughput picodroplet technologies play a vital role in drug discovery by accelerating research in areas such as bispecific antibody development, cell line engineering, and cell therapy.
 
view
download pdf
Human Fresh Tissues vs Clinical Attrition

Graeme Macluskie and Zara Puckrin at REPROCELL

With a multitude of groundbreaking advances in technology, such as molecular biology, cell and material engineering, AI, and machine learning, now is the time to embrace human complexity in drug development.
 
view
download pdf
bullet
In Brief
A Walk in the Cloud

EBR Industry Advisor, Emile Bellott, explores how AI and Big Data in biopharma promise to transform drug development from target identification through to post-market surveillance.
 
view
download pdf
bullet
Features
BIO-Europe® 2021 Digital

EBR speaks to Pam Putz, Managing Director of EBD Group, in anticipation of the BIO-Europe 2021 event and the vital role it plays in building partnerships between global biopharma and investment leaders.
 
view
download pdf
Richter-Helm Triples Production Capacity at Bovenau Site to Meet Global Demand for Biopharma Production

In the continuously growing pharmaceutical biotechnology market, Richter-Helm BioLogics discusses how the expansion of its Bovenau, Germany, site will help them meet the increased demand for production capacities.
 
view
download pdf
Driving Dendritic Cells to Induce Immunity Against the World’s Deadliest Diseases

Christian Brechot at TheraVectys

Used in combination with next-generation gene editing and transduction techniques, lentiviral vectors have the potential to deliver non-replicative, non-cytopathic transduction of the non-dividing dendritic cells that drive cell-mediated responses.
 
view
download pdf
   
spacer


Published quarterly in
January, April,
July, and October

News and Press Releases

Cerevance Establishes Strategic Research Collaboration with Merck for the Discovery of Novel Targets in Alzheimer’s Disease

Boston, MA and Cambridge, UK – AUGUST 9, 2022: Cerevance, a private, clinical-stage drug discovery and development company focused on central nervous system (CNS) diseases, today announced a multi-year strategic research collaboration with Merck, known as MSD outside the United States and Canada, to identify novel targets for Alzheimer’s disease utilizing Cerevance’s proprietary Nuclear Enriched Transcript Sort sequencing (NETSseq) technology platform. Cerevance will concurrently out-license one discovery-stage program to Merck as part of the collaboration.
More info >>

White Papers

Challenges of Analytical Method Transfer in the Pharmaceutical Industry

RSSL

The development and validation of suitable analytical methods is a critical part of the overall drug-development life-cycle. For the majority of products, particularly those that are clinically successful, the transfer of the analytical method between laboratories will be required. This process is designed to verify that a given laboratory is capable of performing a test method for its intended purpose. This can be performed either internally (at the same company), or, with the on-going increasing trend in outsourcing, to an external Contract Research or Development organisation (CRO or CDO).
More info >>

©2000-2011 Samedan Ltd.
Add to favourites

Print this page

Send to a friend
Privacy statement