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European Biopharmaceutical Review

ebr
Autumn 2021

   
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In Brief
The Secret Sauce

Practical and effective lipid nanoparticles are the critical enabling innovation making mRNA-based vaccines a practical reality. EBR Industry Advisor, Emile Bellott, looks at the background of this important advance in materials science and drug delivery
 
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Features
Down the Rabbit Hole: Navigating the Functional Genomics Funnel

Benjamin Borgo at Merck

The power to edit genomes at any scale has revolutionised drug discovery through the ability to create far truer representations of human biology than have ever been available
 
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The Route to Sustainable Procurement

George I’ons at Owen Mumford Pharmaceutical Services

How the biopharmaceutical industry is taking environmental responsibility head-on and forging a path towards a sustainable tomorrow
 
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Orphan Drug Development
 Overcoming Challenges in Orphan Drug Development

Rachel Smith at Veristat

While there is no ‘out-of-the-box’ roadmap for orphan drug development, through a toolkit of innovative solutions, we can address the unique aspects of clinical development in rare diseases, upfront
 
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Advancing Affordable Orphan Drug Development

Haishan Jang at BRIM Biotechnology

Haishan Jang, CEO at BRIM Biotechnology, reveals the biggest challenges of orphan drug development and the significant breakthroughs that are helping the pursuit of innovation
 
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Special Delivery

Sonya Montgomery at Evox Therapeutics

EBR sits down with Sonya Montgomery, Chief Medical Officer at Evox Therapeutics, to discuss how the power of exosomes can be harnessed to overcome the delivery issues in orphan drug development
 
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Antimicrobial Resistance
Diagnostics Leads the Fight Against Antimicrobial Resistance

François Lacoste at bioMérieux

While COVID-19 has been under a spotlight in the last year and a half, the threat of antimicrobial resistance remains critically urgent. Diagnostics could be pivotal in the development of effective solutions and to preserve antibiotic efficacy for future generations
 
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We Are Losing Our Strongest Allies Against Infectious Diseases

Alexander Sturm at Resistell

Antibiotic resistance and antibiotic tolerance are hindering our ability to slow the spread of infectious diseases, and the trends show that this may only be the start of the problem
 
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A Multifaceted Global Approach to Addressing Antimicrobial Resistance

Caroline Forkin at ICON

In a world threatened by AMR, prospects for improving diagnosis, treatment, and prevention could lie in global awareness and collaboration
 
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Biosimilars
Accelerating Biosimilars

Georg Feger at Fresenius Kabi

To ensure patients continue to experience the benefit of biosimilars, a solution to accelerate access will be vital in helping healthcare systems address some of their most critical challenges
 
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Elevate Your Biosimilars Through Branding

Nancy Globus, Manfred Weiler, Justin Holloway, Phil Ford, Andreas Reinbolz, and Jamie Cobb at Syneos Health

When it comes to biosimilars, saying that you are the same is not enough, and the sector is waking up to the realisation that simply offering a lower price is not the effortless road to riches it once may have seemed
 
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Structural Analytical Challenges in Biosimilar and Generic Drug Development

Richard Easton at BioPharmaSpec

The chemistry we perform on biologic molecules to tailor them for our own needs gives rise to challenges in structural analysis that will require technology, experience, and tools to structurally dissect these different classes of drugs
 
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Stem Cell Research and Technology
Regenerative Immunology: A New Era for the Treatment of Autoimmune Conditions

Giovanni Amabile at Enthera Pharmaceuticals

Inflammatory bowel disease and Type 1 diabetes are two autoimmune conditions that could benefit from a new regenerative medicine to rehabilitate specific pathways
 
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Probing Models of Neurological Disease in a Dish Using Multielectrode Arrays

James Ross at Axion BioSystems

Using induced pluripotent stem cells differentiated into neurons that recapitulate diseases, such as ALS and epilepsy, researchers are opening new doors for scientists to model and treat neurological diseases
 
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BIO-Europe 2021 Supplement
Welcome to the BIO-Europe® Digital 2021 Supplement in association with European Biopharmaceutical Review

Pam Putz at EBD Group
 
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Embracing Diagnostics to Hinder Antimicrobial Resistance

Chelsea Brooks at Sysmex Europe

Since the invention of groundbreaking antibiotics, such as penicillin, we have ignored the warning signs that lead to antimicrobial resistance, but it is hoped that new diagnostic tools can add to our growing armamentarium
 
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Innovative Technology Revolutionises Vaccine Development

BioCopy

With vaccine development under the microscope, BioCopy discusses its new molecular copier technology, which offers effective and, above all, fast protection against upcoming pandemics and rapidly changing virus strains
 
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Next-Generation Treatments to Cure Chronic Diseases

Evotec


 
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Pruning the Branches of Rare Cancer

Johanna Bendell at Roche

Oncology patients are faced with universal treatments that often fail to truly understand the complexity of each individual strain of cancer. Professors and doctors from around the world discuss the importance of orphan drugs to suit each disease and every person


 
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The Potential of Pluripotent Stem Cells for ‘Off-the-Shelf’ Cell Therapy

Alessandra De Riva and Eirini Koutsouraki at Mogrify

Human pluripotent stem cells are characterised by their undifferentiated status, infinite self-renewal capacity, and ability to differentiate into any cell type in the body. These characteristics make them an appealing source for therapeutic applications, from regenerative therapy to immuno-oncology
 
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Richter-Helm – The CDMO to Match Your Needs

Richter-Helm

One step ahead – biopharmaceutical production capacity enlargement
 
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Published quarterly in
January, April,
July, and October

News and Press Releases

B Medical Systems launches €15m factory extension in Luxembourg

B Medical Systems (BMS), a global leader in the medical cold chain industry and manufacturer of ultra-low freezers, vaccine refrigerators, freezers, and transport boxes has unveiled a €15m extension at its manufacturing facility in Hosingen, Luxembourg. BMS launched the manufacturing facility in January 2021, which was attended by His Royal Highness Hereditary Grand Duke of Luxembourg, Prince Guillaume.
More info >>

White Papers

Environmental Factors in Data Centres

Dycem

In addition to temperature and humidity, there are many more constraints in the environment that increase failure rates, explains Emilio Sapiña of Secure Techincal Rooms.
More info >>

Industry Events

Pharma Integrates 2021

16 November 2021, VIRTUAL CONFERENCE

Now in its tenth year, Pharma Integrates is a unique event bringing together pharma and healthcare leaders across the Pharmaceutical pipeline to address their needs, to share insights and create debate on crucial topics that influence the future of patient outcomes.
More info >>

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