|
 |
| home > ebr > spring 2004 > in vivo veritas? cell-based assays for identifying rtk inhibitors |
 |
 |
PUBLICATIONS |
European BioPharmaceutical Review
|
| Receptor tyrosine kinases (RTKs) play an important role in many fundamental cellular processes including cell metabolism and survival, as well as cell proliferation and differentiation. Deregulated RTK signalling is critically involved in the development and progression of human cancer. Therefore, RTKs represent attractive targets for anti-cancer therapy. Many methods have been explored to measure the activation and inhibition of RTKs in vitro and in living cells. This article discusses the application of functional cell-based screenings for the identification of specific RTK inhibitors. |
Read full article >>
|
 |
 |
 |
| Rate this article |
You must be a member of the site to make a vote. |
|
Average rating: |
0 |
| | | | | |
|
 |

 |
Industry Events |
 |
Clinical Trials in CNS
25-26 November 2008, Copthorne Tara Hotel, London, UK
SMi present their 7th annual conference… Clinical Trials in CNS 25th to 26th November 2008, Copthorne Tara Hotel, London, UK
More info >> |
|
 |
News and Press Releases |
 |
Aegate Proves Authenticating Drugs at the Point of Dispensing Protects Consumers
More info >> |
|
|