samedan logo
 
 
 
spacer
home > ebr > spring 2004 > how drug hunters become drug engineers
PUBLICATIONS
European Biopharmaceutical Review

how Drug Hunters become Drug Engineers

In the past, one often heard chemists and biologists involved in drug discovery proudly proclaim that they are a 'drug hunter'. Whilst the term 'drug hunter' implies a strong focus of purpose, it also conjures up a picture of an individual with a large calibre rifle from whom the hunted has little chance of escape. In the context of drug R&D, the term 'hunting' is no longer appropriate as it infers that the drug already exists and is just waiting to be found. This may be true when the drug candidate is a natural product, but it is not so for the majority of drug compounds which did not pre-exist but had to be carefully engineered. We would therefore suggest that the term 'drug hunter' is replaced by the term 'drug engineer'. For example, a feature of modern engineering is the use of in silico methods for prototyping and this is also true for drug R&D. An example of this is the variety of computational methods that are now employed to aid drug design from in silico ADMET through to high-throughput docking. However, for these in silico methods to be successful they need to be based on high quality data.

Read full article from PDF >>

Rate this article You must be a member of the site to make a vote.  
Average rating:
0
     

There are no comments in regards to this article.

spacer
By Dr Mark Whittaker, Scientific Director of the Services Division at Evotec OAI Ltd
spacer
Dr Mark Whittaker
spacer
spacer
Print this page
Send to a friend
Privacy statement
News and Press Releases

EUROPEAN CHMP ADOPTS POSITIVE OPINION FOR KITE’S KTE-X19 FOR THE TREATMENT OF RELAPSED OR REFRACTORY MANTLE CELL LYMPHOMA

-- If Approved, KTE-X19 will be an Important New Advance for this Disease with a Poor Prognosis -- -- Kite would Become the First Company with Multiple Approved CAR T Therapies in Europe --
More info >>

White Papers

Personalised Medicine - Pharma and Dx Firms Share Wider Horizons

DiagnostikNet-BB

Personalised medicine might be a popular catch-phrase at the moment, but the term often causes confusion, as there is still no uniform definition for it. The expression can include areas as diverse as the measurement of individual risk, early detection using biomarker testing, stratification of patients suffering from a disease and predictions about its course.
More info >>

 
Industry Events

World Vaccine Congress Europe

18-21 October 2020, Barcelona, Spain

The World Vaccine Congress is an award-winning series of conferences and exhibitions that have grown to become the largest and most established vaccine meeting of its kind across the globe. Our credibility is show through the prestigious scientific advisory board that spend months of hard work creating a new and topical agenda, year on year.
More info >>

 

 

©2000-2011 Samedan Ltd.
Add to favourites

Print this page

Send to a friend
Privacy statement