|
 |
European BioPharmaceutical Review
|
| In the past, one often heard chemists and biologists involved in drug discovery proudly proclaim that they are a 'drug hunter'. Whilst the term 'drug hunter' implies a strong focus of purpose, it also conjures up a picture of an individual with a large calibre rifle from whom the hunted has little chance of escape. In the context of drug R&D, the term 'hunting' is no longer appropriate as it infers that the drug already exists and is just waiting to be found. This may be true when the drug candidate is a natural product, but it is not so for the majority of drug compounds which did not pre-exist but had to be carefully engineered. We would therefore suggest that the term 'drug hunter' is replaced by the term 'drug engineer'. For example, a feature of modern engineering is the use of in silico methods for prototyping and this is also true for drug R&D. An example of this is the variety of computational methods that are now employed to aid drug design from in silico ADMET through to high-throughput docking. However, for these in silico methods to be successful they need to be based on high quality data. |
Read full article >>
|
 |
 |
 |
| Rate this article |
You must be a member of the site to make a vote. |
|
Average rating: |
0 |
| | | | | |
|
 |

 |
Industry Events |
 |
Small Scale Biomanufacturing – clinical trials, cell & gene therapies
18 September 2008, Clifton Pavilion, Bristol Zoo Gardens, Bristol
This one day conference, sponsored by bioProcessUK and organised by BioApproaches South West, will cover key, important topics relating to small scale GMP biomanufacturing.
More info >> |
|
 |
News and Press Releases |
 |
“PACK DIFFERENT” with EMBALLAGE 2008
“Business, Innovation, Outlook” are the watchwords for the 38th World Packaging Exhibition which opens in Paris from 17 to 21 November 2008. Fifteen months before the key packaging event of the end of 2008, EMBALLAGE displays its differences to offer you a new edition that is even more representative, international and rich in new features.
More info >> |
|
|