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European Biopharmaceutical Review

From System Statistics to Systems Biology

With the sequencing of several mammalian genomes, the scientific focus has shifted towards an examination of how static genomes manage to support life in an ever-changing environment. Surprisingly, it is generally recognised that the number of genes does not relate to the genome size or the complexity of the organism. Humans have twice as many genes as C. elegans despite being a number of orders of magnitude more complex than organisms in many respects. Even more puzzling is the fact that we share an almost identical set of genes when compared with chimpanzees, yet our brain processes are much more complex than chimpanzees, a fact mainly attributed mainly to altered transcription control (1).

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By Klaus JW May, Director of Sales and Marketing at Genomatix Software GmbH

Klaus JW May has an MA in Molecular Genetics and a PhD in Macromolecular Force Field Dynamic Simulation and Protein Structural Simulation. From 1984 to 1986 he was Head of European Life Science Applications Division of Evans & Sutherland, Inc, implementing distribution of the first real-time 3-D molecular modelling software 'molecular graphics library'. In 1987 he founded Biosym Europe. In 1995 Klaus moved to May & Partner SciTech Consult as a Senior Partner, consulting in the field of computational chemistry, real-time 3-D graphics, VC technology scouting, where he stayed until 1998 when he became Head of Sales and Marketing at Genomatix.

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Klaus JW May
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