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| home > ebr > winter 2003 > the chemical synthesis of proteins: beyond the genome |
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European Biopharmaceutical Review
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| The pivotal role of proteins in biological processes and disease, and the increasing success of protein therapeutics, has led to the increased development of technologies for their production. In particular, the incorporation of unnatural amino acids and chemical modifications into proteins has enabled a wide variety of derivatives to be rationally engineered for applications in all facets of basic research, drug discovery, diagnostics and therapeutics. The ability to engineer protein sequences in a site-specific manner is thus highly prized and opens up many powerful new avenues. |
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