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European Biopharmaceutical Review

Drug Discovery in the Post-Genomic Era

2003 marked the completion of the human genome project and we now find ourselves in a post-genomic era, trying to understand and utilise a previously unimaginable amount of biological information. Scientists have the daunting task of finding new ways to use the human genome sequence for the benefit of humanity - to develop new drugs and to find better ways to combat disease.

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By Steve Lombardi, Vice President of Corporate Development at Affymetrix, Inc

Steve Lombardi is Vice President of Corporate Development at Affymetrix, Inc. He has made significant progress in moving early-stage, advanced technology out to customers. Prior to joining Affymetrix, Steve was Senior Vice President of Applications and Products for Applied Biosystems, managing strategic marketing and applications R&D. He earned his BA in Biology from Merrimack College.

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Steve Lombardi
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News and Press Releases

Janssen Announces Phase 1 Results for Bispecific Antibody Amivantamab in the Treatment of Patients with Advanced Non-Small Cell Lung Cancer Harbouring Exon 20 Insertion Mutations

BEERSE, BELGIUM, May 18, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced results from the Phase 1 CHRYSALIS study evaluating amivantamab (JNJ-6372) in the treatment of patients with advanced non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) Exon 20 insertion mutations.[i] Amivantamab is an EGFR and MET-targeted bispecific antibody, which targets activating and resistance EGFR mutations, and MET pathway activation.[ii],[iii] Investigators assessed efficacy using overall response rate (ORR) per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST v1.1), duration of response, as well as the safety profile of amivantamab,1 which were the basis of the U.S. Food and Drug Administration (FDA) Breakthrough Therapy Designation granted earlier this year.[iv]
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Industry Events

12th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology

8-11 February 2021, Vienna, Austria

In continuation of the very successful scientific meetings in Budapest, Paris, Berlin, Florence, Geneva, Barcelona, Malta, Istanbul, Lisbon, Glasgow and Granada, the 12th PBP World will be held in Vienna from 8-11 Feb 2021. This every two year held conference has gained an ever increasing impact among the pharmaceutical scientists: With up to 1000 submitted abstracts and about 1300 participants it has become a well-established major meeting, attracting scientists from all over the world.
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