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European Biopharmaceutical Review

MALDI-TOF - The Technique of Choice in Proteomics

Mass spectrometry is now widely viewed as the analytical technique of choice in proteomics. Its popularity has been driven by the high degree of sensitivity it offers and the ability to search data against rapidly expanding protein and expressed sequence tag (EST) databases. The procedure is based on the generation of gaseous ions from analyte molecules, the subsequent separation of these ions according to their mass to charge (m/z) ratio and the detection of these ions.

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By Dr Chris Sutton, Global Business Manager with Kratos Analytical

Dr Chris Sutton is Global Business Manager for MALDI mass spectrometers with Kratos Analytical, part of Shimadzu Biotech. Shimadzu Biotech, a subsidiary of Shimadzu Corporation, is one of the key providers of analytical solutions for life science and drug discovery.

Chris holds global responsibility for MALDI MS business including sales and marketing, applications, engineering and research and development. He is based at the Kratos Analytical facility in Manchester, UK.

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