samedan logo

 
 
spacer
home > ebr > spring 2003 > live cells as drug discovery tools - high-throughput, high-content screening
PUBLICATIONS
European Biopharmaceutical Review

Live Cells as Drug Discovery Tools - High-Throughput, High-Content Screening

In the drug discovery arena, the better the quality of data, the better the chance of striking 'therapeutic gold'. To bridge the gap from candidate compound to blockbuster drug, the assay should mimic the drug target interactions that occur in a living human cell. Traditional screening practices have been based within the non-cellular environment in order to maximise sample throughput and generate simple one-dimensional data. More recently, the advent of low-throughput, high-content systems have allowed more relevant and complex cell-based assays to be performed. However, cell-based, high-content assays and high-throughput screening need not be mutually exclusive - high-information, high-throughput cell-based technologies are available. A new laser scanning system can provide greater insight into the events occurring at the living cell level and pull low-throughput secondary screening assays into the primary screening stage.

Read full article from PDF >>

Rate this article You must be a member of the site to make a vote.  
Average rating:
0
     

There are no comments in regards to this article.

spacer
By Dr Richard Philpott, Managing Director of Acumen Bioscience Ltd

Dr Richard Philpott is Managing Director of Acumen Bioscience Ltd. Graduating from Imperial College, London, Richard completed a sponsored PhD on Steroid Metabolism at CAMR, Porton Down (UK) in 1986. Subsequently he joined the biotechnology division of Alcan International to lead development projects involving sensors, novel separations media and devices.

Following acquisition by Whatman, he transferred to their Maidstone (UK) headquarters as Director of R&D. He joined The Technology Partnership (TTP Group) in March 2001 to lead the formation of Acumen Bioscience Ltd, a wholly owned subsidiary commercialising technologies developed within TTP for drug screening.

spacer
Dr Richard Philpott
spacer
spacer
Print this page
Send to a friend
Privacy statement
News and Press Releases

The renewed Turkish Cargo Web Portal now offers you many conveniences with its new name ‘TK GO’

Turkish Cargo, the fastest-growing brand of the global air cargo industry, updated its web portal; a functional and user-friendly interface on Internet facilitating monitoring of all actions and providing the agents with customized solutions and facilitations.
More info >>

White Papers

8 Ways To Reduce Tablet Manufacturing Costs

Natoli Engineering Company, Inc.

It’s no surprise that in today’s economy, companies are facing budget cuts across the board. In an effort to address these challenges, this list of 8 Ways to Reduce Tablet Manufacturing Costs was compiled.
More info >>

 
Industry Events

2020 Avoca Quality and Innovation Summit

3-4 June 2020, Amsterdam, The Netherlands

The 2020 Avoca Quality and Innovation Summit will take place 3-4 June 2020, in Amsterdam, The Netherlands.
More info >>

 

 

©2000-2011 Samedan Ltd.
Add to favourites

Print this page

Send to a friend
Privacy statement