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| home > ebr > summer 2003 > the potential of zinc ions for prophylaxis and treatment of severe acute respiratory syndrome (sars) |
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European BioPharmaceutical Review
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The discovery that SARS is caused by a coronavirus, related to a group of viruses causing the common cold, may be significant in relation to evidence that zinc ions provide a natural protective mechanism against viruses - especially those such as rhinoviruses that cause respiratory tract infections. The effect of zinc is multi-factorial and is based on direct antiviral effects of zinc ions; amplification and maintenance of immunity; augmentation of interferon activity; and a natural defence mechanism at the cell membrane level. It is suggested that the SARS virus be tested for sensitivity to zinc ions. Because zinc deficiency is a worldwide public health problem, it is worth considering zinc supplementation as a prophylactic and therapeutic measure in the SARS outbreak. In order to maximise zinc absorption and possible local zinc ion action in the buccal cavity, it is suggested that the supplementation should be in the form of 9 to 15mg strength zinc lozenges designed to release divalent zinc ions.
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