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European Biopharmaceutical Review
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Biopharmaceuticals are protein or glycoprotein based drugs. They are high molecular weight molecules. Their therapeutic performance strongly depends on their secondary and tertiary structure that is stabilised mainly by non-covalent, rather weak forces. Changes in structure may lead to loss of therapeutic effect and safety concerns, such as the introduction of immune reactions against the biopharmaceutical.
With their delicate and fragile structure, biopharmaceuticals have to be treated differently than most small organic molecules (SOM) used as drugs. This special treatment not only applies to the different stages of the drug development process, but also to their production and handling by pharmaceutical and medical professionals and, last but not least, the patient (1). In the following contribution the focus will be on the challenges biopharmaceuticals offer to the formulation scientist.
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Industry Events |
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BIO-Europe Spring® 2012 — 6th International Partnering Conference
19-21 March 2012, Amsterdam RAI Convention Center, Amsterdam, The Netherlands
BIO-Europe Spring is the springtime counterpart to EBD Group’s flagship conference, BIO-Europe, and continues the tradition of providing life science companies with high caliber partnering opportunities. Featuring EBD Group’s sophisticated, web-based partnering system, partneringONE®, the event enables delegates to efficiently identify, meet and get partnerships started with companies across the life science value chain, from large biotech and pharma companies to financiers and innovative start-ups.
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