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European BioPharmaceutical Review

Certain Aspects Related to Shareholders' Agreements in Biotech Companies

A biotechnology company and its management have many challenges to face these days. Research projects and the business of the company should constantly progress, but at the same time research-oriented companies need to have balanced finance for expensive research projects. It is often the case that when one financing round is completed the management has to begin planning the next. Private equity investments as well as public subsidies are often the only finance available to start-up biotechnology companies. Loans and credits from banks or other financial institutions are often too expensive sources of financing for these companies. Moreover, start-up biotechs rarely possess the necessary assets to be used as security for the bank's financing. In such cases, venture capital finance plays an important role for biotech companies.


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By Ben Rapinoja, Attorney at Borenius & Kemppinen Ltd

Ben Rapinoja's areas of expertise are intellectual property rights (IPR) - in particular patents, trademarks and contract law. His legal practise relates to the licensing and commercial exploitation of IPR, as well as litigation within patent, trademark and copyright law. Ben advises expanding companies in the biotechnology and pharmaceutical sectors in matters related to corporate law and contracts. He also advises companies with interests in the information technology sector.
Before joining Borenius & Kemppinen, Ben worked at the Ministry of Trade and Industry, gaining experience in IPR law. He was also a Finnish Government representative working with various groups of the European Union Council and Commission, the European Patent Organisation and international organisations specialising in IPR (such as WIPO and WTO).

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Ben Rapinoja
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Industry Events

4th Annual Patient Recruitment and Retention in Clinical Trials

13-15 October 2008, Amsterdam

Patient recruitment is now consuming thirty percent of clinical trial time - more time than any other clinical trial activity - and almost half of all trial delays result from patient recruitment problems. As the recruiting culture becomes more sophisticated and the forces affecting patient enrollment grow more numerous and complex, pharmaceutical companies are striving to discover new strategies to facilitate enrollment in clinical trials. With increasing industry pressure to develop, test and market greater numbers of new drugs faster, pharmaceutical companies need to perform clinical trials as quickly as possible. Inefficient patient recruitment processes is a formidable barrier to pharmaceutical companies' success in launching new products. Improving the patient recruitment process is imperative to avoid wasted investments and eliminate costly delays in bringing new drugs to market -- today and even more so in the not-so-distant future. Improved patient recruitment presents one of the largest opportunities for pharmaceutical companies to eliminate delays in clinical trials, thereby making it possible to reduce time to market.  With patent time limits and large overheads meaning that any delays in the development timeline can be disastrous, a good understanding of how to successfully recruit patients for trials is vital for any company looking to succeed.
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News and Press Releases

Azopharma Announces Plans to Implement XcelodoseTM Technology in the Production of Early Stage Clinical Trial Materials

HOLLYWOOD, Fla. – Azopharma Product Development Group, Inc. (“Azopharma”) announced today plans to implement Xcelodose technology at its formulations development facility, ApiCross Drug Delivery Technologies. Xcelodose technology is a powder micro-dosing system developed by Meridica. This technology offers a unique powder dispensing system for small-scale capsule filling and ultimately assists in conserving valuable research material as well as reducing various Preformulation activities.
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