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European Biopharmaceutical Review

Intelligent Software Serving Control and Supervision of Fermentation Processes

Fermentation processes are becoming increasingly sophisticated. In order to automate the entire operation and to obtain complete traceability of the process, bioinformatics are implemented within the fermentation equipment and represent an important part of it. 'Sequences' are functions of the 'Rhapsody' software and represent a series of commands designed to control a fermentor without operator intervention. They perform a collection of actions and decisions that an operator would perform if running the fermentor manually, 24-hours-a-day. Sequential programming enables automatic configuration of control loops and supervision during the fermentation process. Before designing sequences, it is necessary to define the fermentation strategy. This strategy may be simplified or elaborated to suit the requirements of any fermentation process.


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By Doru Felezeu, International Director at the Biolafitte & Moritz Division of Pierre Guerin

Doru Felezeu, Dipl. Ing., is International Director at Biolafitte & Moritz in Mauzй, France. Doru graduated in Medical Electronics from the Polytechnic School of Timisoara in 1980 and has been with Biolafitte since January 1991.
His studies included two years within an exchange programme at the California State University, Berkeley. During his 11 years at Biolafitte, Doru has been the Head of the R&D department and involved in the development of new 'intelligent software' and equipment, from laboratory to pilot and industrial scale.

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Doru Felezeu
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