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There are two essential steps at the beginning of the process of bringing a drug compound to market; the identification of a lead compound, and the optimisation of this lead compound to hone the required characteristics - including its affinity - for its specific target. The modern pharmaceutical industry is involved in a continuous search for ways of streamlining these two steps to increase yields, save time and reduce costs. As a result, there has been a pressure to develop the capabilities of instrumentation to assist in these processes. The recent revolution in the development of calorimetric instrumentation (and its applications) has enabled it to assume a position in the frontline of the battle to develop pharmaceutical products. |
