spacer
home > ebr > summer 2008 > dealing with the deluge
PUBLICATIONS
European Biopharmaceutical Review

Dealing with the Deluge

Flow cytometry is a technique for cell characterisation that is popularly used in basic and translational research for understanding, for example, how mutated stem cells may confer therapy resistance to a tumour (1). Alternatively, cell characterisation can be used to measure cell receptors during activation or as a response to immunosuppressive drugs. A flow cytometer consists of a narrow, hydrodynamically-focused stream of cells that pass and are interrogated by a light source. The cellsí physical characteristics of size and granularity, as well as any fluorescent labels attached in or on the cells, scatter the beam of light. Fluorescent labels attached will then be excited, enabling the appropriate emission characteristics to be measured in relative terms of fluorescent intensity.

Flow cytometer manufacturers have responded to the needs of modern researchers by developing faster systems that can measure more variables over shorter time periods for applications such as detecting tumour cells in peripheral blood and examining different aspects of stem cell differentiation. However, the ability of the software that flow cytometers rely on to analyse and visualise the rapidly rising tide of data now being generated has lagged way behind these improvements in instrument technology. This article examines some of the approaches that enlightened software manufacturers are now taking to speed up and simplify data analysis and support the revolution in flow cytometry research.


Read full article from PDF >>

Rate this article You must be a member of the site to make a vote.  
Average rating:
0
     

There are no comments in regards to this article.

spacer
Gillian Byrne is the Product Specialist of Applied Cytometry. Gillianís responsibilities include establishing and maintaining expert technical knowledge of the companyís products and determining the market needs for effective product launch strategies. She plays an active role in developing business relationships with customers of the flow cytometry industry as well as displaying her expert product knowledge at global industry related events. As a biomedical science graduate, Gillianís career was mainly spent in the public sector before venturing into the private sector, working as a state registered biomedical scientist for a clinical microbiology laboratory. Here she gained valuable skills in all aspects of bacteriology, serology and molecular biology, giving her first hand experience of the biomedical industry.
spacer
Gillian Byrne
spacer
spacer
Print this page
Send to a friend
Privacy statement
News and Press Releases

Wellcome Trust Centre for Human Genetics and Genomics plc first to sequence multiple human genomes using hand-held nanopore technology


More info >>

White Papers

The Process of Informed Consent (written by ACRP)

CenterWatch

Every investigator and clinical research coordinator (CRC) should recognize the importance of obtaining valid and appropriate informed consent as an important protection of the rights and welfare of human subjects. The purpose of this ACRP guidance document is not to provide a literature review or summarize the recommendations of various working groups. Instead, the Association decided it would be helpful to provide short and focused guidance which describes how to best structure the informed consent process in accordance with best practices.
More info >>

 
Industry Events

Pharmaceutical Microbiology East Coast

13-14 November 2017, Renaissance Woodbridge Hotel, New Jersey

Drawing on from the huge success of SMiís Pharmaceutical Microbiology event series, SMi is delighted to announce the launch of Pharmaceutical Microbiology East Coast. Being the eighth in its series, this event will take place in New Jersey, USA, on November 13th and 14th 2017. Aimed at Microbiologists, Quality Control and Quality Assurance Managers, Pharmaceutical Microbiology East Coast 2017 will address the best practices for rapid microbial and sterility testing and tackle the challenges of contamination control.
More info >>

 

 

©2000-2011 Samedan Ltd.
Add to favourites

Print this page

Send to a friend
Privacy statement