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European Biopharmaceutical Review
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Flow cytometry is a technique for cell characterisation that is popularly used
in basic and translational research for understanding, for example, how mutated
stem cells may confer therapy resistance to a tumour (1). Alternatively, cell
characterisation can be used to measure cell receptors during activation or as
a response to immunosuppressive drugs. A flow cytometer consists of a narrow,
hydrodynamically-focused stream of cells that pass and are interrogated by a light
source. The cells’ physical characteristics of size and granularity, as well as any
fluorescent labels attached in or on the cells, scatter the beam of light. Fluorescent
labels attached will then be excited, enabling the appropriate emission
characteristics to be measured in relative terms of fluorescent intensity.
Flow cytometer manufacturers have responded to the needs of
modern researchers by developing faster systems that can measure
more variables over shorter time periods for applications such as
detecting tumour cells in peripheral blood and examining different
aspects of stem cell differentiation. However, the ability of the
software that flow cytometers rely on to analyse and visualise the
rapidly rising tide of data now being generated has lagged way
behind these improvements in instrument technology. This article
examines some of the approaches that enlightened software
manufacturers are now taking to speed up and simplify data
analysis and support the revolution in flow cytometry research. |
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News and Press Releases |
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E Ink and Faubel Unveil the Med Label to Revolutionize the Clinical Trial Supply Chain
E Ink® Holdings, "E Ink" (8069.TW), the leading innovator of electronic
ink technology and Faubel & Co. Nachf. GmbH, a proven supplier to
the pharmaceutical and chemical industry, announced the availability of
the Faubel-Med® Label, a smart label for investigational medicinal
products. The Med Label features E Ink’s low-voltage film technology,
bringing display modules and new system designs to pharmaceutical
packaging.
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White Papers |
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The EC Definition of a Nanomaterial - Potential Measurement Methodologies
NanoSight
In October 2011 the European Commission
published a definition of Nanomaterials. This move followed more than six
years of scientific consideration of the potential toxicological and
environmental challenges posed by engineered nanomaterials.
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Industry Events |
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T3: Trials, Tech and Transformation
30-31 May 2018, Raleigh Convention Center, Raleigh, NC
T3
is back for 2018 to provide you with the latest updates and top tips from
across the clinical trials landscape. Connecting leading experts, influencers and innovators from pharma,
biotech, CROs, patient advocacy groups, academia and beyond, T3 is themeeting place for all stakeholders to
voice their questions, connect with peers, and get direct feedback from an
expert speaker line-up.And this
year, we're in Raleigh.
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