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Pharmaceutical Manufacturing and Packing Sourcer

pmps
Spring 2009
At the cutting edge of the latest industry developments, Samedan is adept at keeping the information you need at your fingertips. PMPS provides a unique platform of communication for the market across Europe, North America and the rest of the developed world. To find out what's hot in the world of pharmaceuticals, take a look below at the range of articles featured in this issue of PMPS.
   
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Manufacturing
Accenture's Global Pharma Industry Supply Chain & Tech Ops Study is investigating the latest macro trends across the pharmaceutical supply chain. Jay Welsh reports on the findings of the first wave of the study, concluding that there are a number of areas where processes can be streamlined.  
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Lyophilisation is often called for at a number of stages during the manufacturing process. Antonello A Barresi, Davide Fissore and Roberto Pisano at Politecnico di Torino present ways in which freeze-drying processes and recipes can be improved.  
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Aseptic processing is crucial for manufacturers wishing to guarantee product safety. Chuck Reed at Weiler Engineering, Inc introduces blow-fill-seal technology, and compares it to traditional methods of aseptic processing.  
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One of the roles of a manufacturer is to provide the first link in the crucial chain of product security. Diethard Schaefer at Schreiner Medipharm reveals how manufacturers ensure that they fulfil this role.  
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Continuing to look at the role of the manufacturer within the supply chain, Matthew Ottoway at Univar explores the options for distribution of pharmaceutical products.  
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Cool Chain, Cargo & Logistics
Passive cooling systems self-sufficiently maintain product temperature, without the need for electrical power. Developing such a system is a complex process and, argues Geraint Thomas at Laminar Medica, can be significantly aided by thorough preliminary research.  
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The journey by air can be particularly precarious for temperature-sensitive drugs, compared with road or sea logistics. Jonathan Neeld of CSafe updates us on the latest developments in air container technology, which can keep your products safe during flight.  
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Solid carbon dioxide - better known as dry ice - is commonly used in cold chain shipping, but is a potentially hazardous material. Karl Schlenker at Minnesota Thermal Science describes an incident which brought this safety concern into sharp relief, and outlines ways in which such accidents can be avoided.  
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The FDA's e-transformation initiative seeks to develop a system in which all regulated product information is stored electronically. Daniel R Matlis at Axendia explores the initiative, and outlines what it will mean for pharmaceutical companies.  
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Drug Delivery 
Michael N Eakins of Eakins & Associates discusses how manufacturers of glass products for parenteral delivery can maintain quality in their production line while building plants in a number of different countries.  
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The battle for patient compliance occurs at several points along the supply chain. Tassilo Korab at the HCPC Europe presents packaging strategies that can help win the fight.  
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Formulations, Ingredients and Excipients
Specially formulated excipients are often needed to hold together the active ingredients of a drug. Katleen Brys at Cargill Excipients discusses glucose monohydrate and its role as a binder in roller-compacted tablets.  
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PACKING, PACKAGING & ANTI-COUNTERFEITING
Bikash Chatterjee at Pharmatech Associates, Inc introduces e-pedigree: an integrated approach to track-and-trace, which seeks to promote security in the pharmaceutical supply chain.  
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Serial numbers have a crucial role to play in product security, uniquely identifying any given drug package. Joe Ringwood at Systech International analyses the benefits of a well-developed serialisation strategy.  
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CONTROLLED RELEASE
HIV/AIDS presents one of the most considerable challenges to scientists and pharmacists alike. Rhonda M Curran at Queen's University Belfast suggests that controlled release might hold the key for potentially revolutionary HIV-1 prevention drugs.  
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A significant number of oral controlled release solutions use degradable polymers; Aylvin A Dias and Marc Hendriks at DSM Biomedical look at the growing significance of this technology in the field.

 
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The formulation challenges facing manufacturers of adhesives for transdermal patches are considerable. John O'Mahony of Adhesives Research Ireland Ltd takes us through the factors that manufacturers need to consider in this market.  
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Mark Bünger at Lux Research offers a broader perspective on controlled release, examining the investments and partnerships that have been precipitated by the latest innovations in this sector of the industry.  
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Edited by
Robert Harris
Chief Technical Officer at Juniper Pharma Services
Published quarterly in
February, May,
August and November

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