samedan logo
 
 
 
spacer
home > pmps > spring 2009 > transdermal technology
PUBLICATIONS
Pharmaceutical Manufacturing and Packing Sourcer

Transdermal Technology

Transdermal drug delivery systems (TDDS) are widely proven and accepted forms for predictable and reproducible drug delivery. TDDS bypass the hepatic first-pass effect and potential gastrointestinal side effects of oral dosage forms, as the drug is absorbed directly through the skin for delivery to the blood or lymphatic system. Treatment is quickly and easily terminated if toxicities (such as drug allergies) occur, simply by removing the patch. This drug delivery platform improves patient compliance for chronic or maintenance treatments by virtue of its ease of use, fewer side effects, relatively low cost in comparison to alternative devices, and minimal risk of trauma or infection (1).


Read full article from PDF >>

Rate this article You must be a member of the site to make a vote.  
Average rating:
0
     

There are no comments in regards to this article.

spacer

John O’Mahony, PhD, is a Senior Scientist and team leader with Adhesives Research Ireland Ltd, where he is responsible for the development of new products for the company’s medical and pharmaceutical business units. John holds a degree in Material Science from Trinity College Dublin and a PhD in Chemical Engineering, specialising in polymer characterisation, from the University of Queensland, Australia. John has previous experience in polymer development at the National Microelectronic Research Centre, University College Cork, and as a Senior Research Scientist at ICI Chemicals and Polymers division in Runcorn, UK.

spacer
John O’Mahony
spacer
spacer
Print this page
Send to a friend
Privacy statement
News and Press Releases

Europital launches as a science-driven full service CRO

Europital – a globally-focused full service CRO serving small and mid-tier innovators – announces a significant expansion as it launches new capabilities across project management, clinical monitoring, biostatistics, pharmacovigilance, regulatory affairs and data management, in addition to its existing services of Medical Affairs and Medical Writing.
More info >>

White Papers

Extractables and Leachables Testing: A Risk Based Approach

RSSL

Pharmaceutical products are in contact with many external components during both manufacture and usage and small amounts of chemicals may leach from these components with a potential health risk to the patient. Extractables and leachables (E&L) studies therefore play an important role in verifying the safety of a drug product over its lifetime. Regulatory organisations such as the US Food and Drug Administration (FDA) and the European Medicines Agency (EMEA) are taking an increased interest in the interactions of various drug delivery devices, pharmaceutical product containers and medical devices with drug product and/or patient and this field is therefore growing in importance. Regulatory guidelines indicate that an extractables profile should be determined for all materials that contact the drug product. Once established, this profile can be used to determine whether any of these extractables are present as leachables within the product. If a leachable is detected, amounts can be determined using validated analytical methods, after which a biological risk can be established based on the exposure. This white paper will provide an overview of the processes used to determine extractables and leachables from plastics.
More info >>

 
Industry Events

World Vaccine Congress Europe

18-21 October 2020, Barcelona, Spain

The World Vaccine Congress is an award-winning series of conferences and exhibitions that have grown to become the largest and most established vaccine meeting of its kind across the globe. Our credibility is show through the prestigious scientific advisory board that spend months of hard work creating a new and topical agenda, year on year.
More info >>

 

 

©2000-2011 Samedan Ltd.
Add to favourites

Print this page

Send to a friend
Privacy statement