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The technologies underpinning inhaled drug delivery have developed rapidly over the past decade as the pharmaceutical industry has moved to exploit the lungs as a route to rapidly introducing therapeutics into the body. Many locally acting and systemic drugs are now routinely delivered in this way. However, developing delivery devices and formulations that perform well is challenging, and is an area of continuing investment for the industry.
It seems timely, therefore, to review the evolution of delivery devices and the benefits provided by different designs as a prelude to considering key performance targets for inhalation systems and the in vitro analytical techniques used to ensure they are met. |
