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home > pmps > Winter 2014
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Pharmaceutical Manufacturing and Packing Sourcer

pmps
Winter 2014

   
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Industry Insight 
Industry Insight

Editor Graham Hughes highlights the importance of manufacturing and packaging to the pharma industry, before considering a selection of articles from this edition of PMPS.
 
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STERILE PACKAGING
Metal Contamination

Making a Material Difference


While plastic packaging has the edge over glass in terms of its resistance to breakage, light weight and durability, trace amounts of contaminants can drastically affect a product's quality, say Rodolfo Merola and Robert Scott at Thermo Fisher Scientific.


 
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Protein Aggregation

Under Stress


How does protein aggregation in glass vials compare to that of plastic cyclic olefin polymer containers? Lloyd Waxman, Vinod Vilivalam and Dennis Liu from West Pharmaceutical Services investigate the best packaging for therapeutic proteins.
 
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Anti-Counterfeiting
Serialisation Security

Keeping Track


With falsifi ed medicines proving a constant threat to patient safety, Ian Parsonage at Packaging Coordinators believes that implementing a global approach, alongside the use of innovative overt and covert technology, is the best way to combat counterfeiting.
 
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LOGISTICS
Environmental Waste

Total Recall

Farzad Henareh
from Stericycle ExpertSOLUTIONS talks us through the most efficient way of handling a product recall. He explains that greener methods of disposal are key to protecting the public, the environment and, ultimately, your company brand.
 
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CLEANROOMS
Rotational Cleaning

Line of Attack


The most effective way of preventing resistant strains of bacteria developing in your cleanroom is to use two or more disinfectants in rotation, thereby maximising the kill spectrum, advises Rebecca Smith at Connect 2 Cleanrooms.
 
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PACKING & PACKAGING
Polyolefin Resins

Plastic Power


Alessandro Guidicini and Alexander Woerz at LyondellBasell consider the cornerstones of service you should expect from a new plastic resin provider, which includes evaluating the right material and grade required for your healthcare packaging needs.
 
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Thermoplastic Elastomers

The Pressure is Off


Replacing traditional vulcanised rubber materials with thermoplastic elastomers could result in higher productivity and lower system costs, advises John Voyce from Polyone GLS Thermoplastic  Elastomers.
 
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Child Resistant Packaging

Defence Mechanisms

One of the biggest risks to children in the home is unintentional pharmaceutical poisoning. Marek Miszczak and Christina Desirée Holder at Gerresheimer champion the development of child-resistant packaging, while stressing that senior citizenfriendly designs must also be considered.
 
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Printing Trends

Packing a Punch


Four contemporary design trends are pushing the limits of what packaging manufacturers can deliver, but a balance between creativity and technology must be struck. Domenick Pasqualone from LPS Industries reports.
 
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NUTRACEUTICALS
Nutraceutical Manufacturing

On Top Form


Detailed design is crucial to creating a successful nutraceutical product in tablet form, but overcoming strict regulations, patient demands and manufacturing complications is no easy task, reveal Rob Blanchard and Trevor Higgins of I Holland.
 
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FLUID SYSTEM TECHNOLOGY
Thermal Fluid Maintenance

Liquid Assets


The hidden transfer of energy to the production process is often overlooked. However, Global Heat Transfer’s Clive Jones warns that an awareness of the correct methods of thermal fluid maintenance can prevent costly breakdowns and delays.
 
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MANUFACTURING & PROCESSING
Supply Chain Relationships

Linking Up

Graham Dewhurst,
Director General of the Manufacturing Technologies Association, advocates better collaboration, communication and trust between pharma companies and their outsourcing partners to achieve a stronger supply chain.
 
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Overall Equipment Effectiveness

Steps to Success


Overall equipment effectiveness is an established method for production improvement. Roland Pichler at Bosch Packaging Technology describes how it can work for pharma.
 
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API Manufacturing: India

Capacity for Growth

Pradeep Kasirajan
at Beroe predicts that by improving utilisation rates in Indian active pharmaceutical ingredient manufacturing facilities, standard operating costs will decrease. But will this result in a price drop?
 
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Manufacturing Challenges

Take Control


Growth within pharma manufacturing is predicted to be slow over the next five years. To boost this progress, Alan Johnston at Siemens Industry suggests three primary operational drivers which are currently influencing the sector.
 
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ROBOTICS & AUTOMATION
Robotic Solutions

A Helping Hand


Recent studies suggest that the long-awaited move towards robotic technology is starting to take place. Chris Sumner at FANUC outlines the many potential benefits implementation could have for the pharma industry.
 
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The End of the line
The End of the Line

Star Product

A good developer will understand the way in which product packaging is handled and perceived. Richard Harrop explains how to achieve a five-star service.
 
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Edited by
Randice Altschul
Chief Executive Officer at Pop Test and Palisades Therapeutics

Published quarterly in
February, May,
August, and November

News and Press Releases

Pharmaceutical Packaging and Labelling Summit in Zurich; ACG presentation

At next week’s Pharmaceutical Packaging and Labelling Summit in Zurich (18-19 June), Dr. Eugen Hertel from ACG will be speaking on: Challenges for Global Pharma companies to Implement Anti-Counterfeit Strategy for Russian Track & Trace Regulation. This presentation will include details around ‘the fight against counterfeit medicine - there have been and still are worldwide initiatives to make the supply chain and the safety of medicines secure. After large markets such as the USA and Europe passed their laws and regulations for the pharmaceutical manufacturing companies and established the IT infrastructure, Russia is now next on the move.
More info >>

White Papers

Syringe siliconization

Gerresheimer AG

Ready-to-fill, i.e. sterile, prefillable glass syringes, are washed, siliconized, sterilized and packaged by the primary packaging manufacturer. They can then be filled by the pharmaceutical companies without any further processing. These days the majority of prefillable syringes are made of glass and the trend looks set to continue. The siliconization of the syringe barrel is an extremely important aspect of the production of sterile, prefillable glass syringes because the functional interaction of the glass barrel siliconization and the plunger stopper siliconization is crucial to the efficiency of the entire system. Both inadequate and excessive siliconization can cause problems in this connection. The use of modern technology can achieve an extremely uniform distribution of silicone oil in glass syringes with reduced quantities of silicone oil. Another option for minimizing the amount of free silicone oil in a syringe is the thermal fixation of the silicone oil on the glass surface in a process called baked-on siliconization. Plastic-based silicone oil-free or low-silicone oil prefillable syringe systems are a relatively new development. Silicone oil-free lubricant coatings for syringes are also currently in the development phase.
More info >>

Industry Events

SAPHEX 2019

23-24 October 2019, GALLAGHER CONVENTION CENTRE, 10 RICHARDS DRIVE, HALFWAY HOUSE, MIDRAND, 1685, SOUTH AFRICA

SAPHEX 2019 will be held on the 23rd-24th October at the Gallagher Convention Centre, Johannesburg, South Africa.
More info >>

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