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Pharmaceutical Manufacturing and Packing Sourcer

pmps
Winter 2017

   
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Industry Insight 
Industry Insight

PMPS Industry Advisor Robert Harris comments on how companies can remain competitive by insourcing and how the cold chain logistics has grown in order to handle the expanding biologics market as he introduces this edition.
 
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Manufacturing
Insourcing and Productivity

Look Inside

AMRI’s
Michael P Trova and Joachim Kaus reveal the benefits of insourcing and how it can help to control internal R&D. As outsourcing continues to become more expensive, perhaps this is a cost-effective way to maximise productivity?
 
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Outsourcing APIs

Made in Europe


Companies are persistently shifting their outsourcing to firms in China and India, leaving European contract manufacturing organisations with a need to find new ways to attract business. Farmak’s Jiri Raska explores the advantages of hiring a European firm over the budget-friendly Asian firms.
 
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Central and Eastern European CDMOs

Watching the East


In recent years, the demand for contract service providers in Central and Eastern European countries has grown. With a particular focus on Slovakia, Anthony Sheehan at Saneca Pharma highlights the reasons behind this and assesses the European market.
 
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Drug Delivery 
Drug Delivery Devices

What’s the Outcome?

Bill Welch
at Phillips-Medisize discusses why so many companies are beginning to outsource device designing and manufacturing. Strong plans are important for the patient and tactful partnerships, he says, are key.
 
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Formulations, Ingredients and Excipients
Solid Formulations

Vanishing Act


Developing formulations to effectively deliver pharmaceuticals into the body is often a challenge, notes Juniper Pharma Services’ Robert Harris. There are, however, several options to rectify this. He considers various approaches to improve the drug solubility of amorphous solid dispersions.
 
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Inhalation Aerosols

Formulating a Plan

Poonam Aliyah Sheth
and Ramil Menzeleev from Recipharm explore why inhalation formulations are important in the drug delivery landscape and share their liquid chromatography method with ultraviolet detection and mass spectrometry.
 
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INTERVIEWS
Q&A: Primary Packaging

Made of Glass

PMPS interviews Jens Heymann at Gerresheimer about the company’s glass production. As plastic begins to become an attractive alternative, Jens gives his views on why glass will continue to be one of the most popular materials for primary packaging.
 
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Q&A: GDP Compliance

Reach for the Sky


PMPS interviews Peter Musola of Kenya Airways Cargo to illustrate how the company ensures Good Distribution Practice to achieve better compliance with regards to the cold chain. With the African air network expanding, Peter describes the challenges and pitfalls of creating a network on the continent.
 
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PARENTERALS
Pre-Filled Syringes

Innovative Manufacturing Technologies


The generation of glass particles inevitably leads to recalls and products being withdrawn from the market. Philippe Lauwers and Matteo Falgari at Nipro PharmaPackaging suggest two ways to combat this problem: laser assisted cutting and X-ray needle shield inspection technology.
 
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PACKING & PACKAGING
Packaging Trends

Compliance Made Easy

Smart pharmaceutical packaging has evolved to aid patient adherence; what are the roles of this commodity and the cloud in this ongoing challenge? Information Mediary Corporation’s Allan Wilson investigates.
 
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MACHINERY
Tablet Production

Tools of the Trade


Although they are one of the most popular dosage types, compressed tablets can be tricky to create. Steve Osborn at I Holland proposes multi-tipped tools to increase production capacity and make manufacturing lines more cost-effective without decreasing output.
 
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COOL CHAIN
Cold Chain Logistics

Play it Cool


A lot of companies look to logistics and the cold chain to save money, but the approaches taken do not always achieve the greatest results. Dr Jean-Pierre Emond and Melissa Germain at The Illuminate Group present tailor-made, innovative techniques that could be the answer.
 
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Supply Chain
Collaborative Supply Chains

Working Together


Due to stringent guidelines as well as scientific and technological advancements, the pharma supply chain is becoming increasingly difficult to navigate. Darren Halford of EU Automation contemplates the importance of data and a cooperative method.
 
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The End of the line
End of the Line

Out With the Old


The world is poised to change in 2017, and the pharma sector is following suit. PMPS Industry Advisor Robert Harris ponders over Brexit and how US healthcare could be transformed under President Trump.
 
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INHALATION TECHNOLOGY SUPPLEMENT
Foreword

Sparking Innovation


Richard Dalby and Pierre Carlotti, co-organisers of RDD Europe 2017, introduce this special supplement on inhalation technology.
 
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Event Preview

Breathing In

This year’s Respiratory Drug Delivery conference taking place in Nice, France, promises first class innovations and scientific content. Find out how to register and what is in store at RDD Europe 2017.
 
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Inhaler Design

Thinking Human


Julian Dixon at Team Consulting highlights why medical device companies should listen to the end user when designing their products. Human factor analysis could be the crucial element in creating inhalers that are simple and easy to use.
 
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Spray Drying

Sizing Up

Although the lung is an attractive target for drug delivery, there are still some challenges to overcome. According to Capsugel’s Devon B DuBose, there are a number of approaches that can be taken to overcome them.
 
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Smart Inhalation

Left to Your Own Devices


While advances have been made in developing novel therapies, their benefits often go unrealised due to poor adherence, say Dana Shears at H&T Presspart and Melissa Manice at Cohero Health. Perhaps novel devices could enable patients to see the advantages of their treatment.
 
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Market Analysis

Breathing Space


No matter what type of inhaler a company manufactures, it can be difficult to keep up in the ever-changing drug delivery market. Rajiv Kalia, Ruchika Kakarya and Pooja Ganguly at MarketsandMarkets provide an overview, with particular focus on the Asia-Pacific region.


 
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Device Training

Inhalation Education

Noble’s Craig Baker
shares his solution to improve patient compliance in pulmonary drug delivery: training. The use of smart devices with inhalers could be the answer to achieving positive results and establishing brand loyalty.
 
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Edited by
Randice Altschul
Chief Executive Officer at Pop Test and Palisades Therapeutics

Published quarterly in
February, May,
August and November

News and Press Releases

Bigneat is awarded the Queen’s Award by Lord-Lieutenant of Hampshire

Bigneat Ltd, winner of a Queen’s Award for Enterprise earlier this year, received their Award from Nigel Atkinson Esq, HM Lord-Lieutenant of Hampshire on 16th October at the Bigneat factory in Waterlooville.
More info >>

White Papers

Nanoparticle Tracking Analysis. A Review of Applications and Usage in the Analysis of Exosomes and Microvesicles

NanoSight

The study of exosomes and other cell-derived microvesicles is an area of rapidly growing importance and the subject of intense interest and research. The previous lack of suitable methods for their detection, analysis, enumeration and phenotyping is proving to be a significant limitation in these studies. This mini-review shows the degree to which the technique of Nanoparticle Tracking Analysis (NTA) is helping to address these problems.
More info >>

Industry Events

14th World Advanced Therapies & Regenerative Medicine Congress 2018

16-18 May 2018, Business Design Centre, London, United Kingdom

In May 2018 the World Advanced Therapies & Regenerative Medicine Congress, will bring together 800+ attendees and explore the rapidly developing world of ATMPs (Advanced Therapy Medicinal Products).
More info >>

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