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Pharmaceutical Manufacturing and Packing Sourcer

Compliance Made Easy

We have come a long way from the days of the neighbourhood apothecary, grinding and mixing ingredients to treat things he himself might have diagnosed, and for which he would follow the healing process. The apothecary took a hands-on role in healthcare, because it has long been known that patients have poor adherence records with medication and that noncompliance is a huge source of error when determining a treatment’s effectiveness. This has, therefore, been the driver for packaging initiatives.

The idea of measuring medication compliance electronically was pioneered by Aardex with smart vial caps over 20 years ago. These record the opening and closing of the vial cap as a proxy for medication taking, but are subject to the limitation that the patient can take any number of tablets or capsules from the vial during a single opening.

Smart Blister Packages

The blister package was patented in 1947 as a means of facilitating medication compliance, but sat on the shelf for almost 50 years before making its appearance in the clinical marketplace. Despite this long wait, the claim that blister packaging would improve patient adherence has never been demonstrated due to the lack of a means of measuring this accurately. However, there have been extensive efforts to make the use of this format safer and more user-friendly, for which a number of Health and Care Professionals Council awards have been given.

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Allan Wilson, MD, PhD, co-founded Information Mediary Corporation in 2002 and now devotes his time to the study of medication compliance. He has worked as a consultant in the healthcare field for both public and private sectors, and his research interests lie in clinical pharmacology, biotechnology and large data systems. Allan was Professor and Head of the Section of Addiction Psychiatry at the University of Ottawa, Canada, for more than 25 years.
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Allan Wilson
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