spacer
home > pmps > winter 2018 > protective properties
PUBLICATIONS
Pharmaceutical Manufacturing and Packing Sourcer

Protective Properties

Coating technology has advanced considerably over the years. When used in conjunction with highquality tooling steel, tool coatings are increasingly seen as an acceptable means of solving production problems. They allow for better tableting efficiency and output by reducing the requirement for tools to be taken out of production for additional cleaning and maintenance work to remove problematic residue, which, if left untreated, may cause potential production issues, such as sticking and picking.

Understanding the product being compressed is crucial when it comes to choosing a tool coating. Some formulations are particularly abrasive and can cause adverse effects to the punch tips when under compression, causing wear, pitting, or corrosion. Although tools are manufactured from hardened and tempered tool steel, the demanding processes involved can lead to deterioration if the tool material is not optimised along with a relevant coating.

The need for a coating that will improve the hardness of the tooling is extremely important for particular formulations. Some ingredients have high quantities of hard, sharp-edged minerals that, when repeatedly compressed, can scrape away or penetrate the surface of the tool. The abrasion can lead to the erosion of punch tip detail such as logo embossing and other identification and branding. Eventually, this wear will lead to weight variation and sometimes other issues like sticking, resulting in the scrapping of the punch.

Read full article from PDF >>

Rate this article You must be a member of the site to make a vote.  
Average rating:
0
     

There are no comments in regards to this article.

spacer
Since joining the company in 2003, Rob Blanchard – Research Development, and Quality Systems Manager – has been instrumental in the development of I Holland’s range of surface treatments and coatings for tablet compression tooling. He is also part of the Eurostandard steering committee and responsible for I Holland’s registration to ISO 9001:2015. Rob also co-ordinates I Holland’s close collaboration with various respected academic research bodies.
spacer
Rob Blanchard
spacer
spacer
Print this page
Send to a friend
Privacy statement
News and Press Releases

Teknomeks new tall cupboards elevate hygiene levels

Hygienic furniture specialist Teknomek has introduced a new range of cupboards developed with time and risk in mind. The robust units are designed to fit into SOP and reduce cleaning times, whilst eliminating trap points where dirt and contaminants could build up.
More info >>

White Papers

Conveying Medical Guidance in Clinical Trials – A Survey

Europital Medical Consultancy

With the incremental demand for proactive safety surveillance throughout the conduct of clinical trials, the role of Medical Management is at the fore in ensuring the safety and wellbeing of the participants. The complex responsibilities of a Medical Monitor (MM) starts from the design and development phase, through to study close out. Understanding the principle behind the protocol and the prospective medical solution the study would deliver forms the bloodline for the MM role. Often, the MM is the face of contact for both the site personnel and the study team members with regard to medical, safety and scientific issues within the project. When it comes to medical guidance, the communication channel used to deliver solutions contributes to a large extent in effectively managing decisive situations. Our previous study on acquiring medical guidance from an operations team perspective revealed that e-mails were the most used communication method (see the article, 'Talking Points', in ICT November 2014). In our efforts to further strengthen the mode of medical guidance delivery, we designed a survey to study the existing trend and constraints in this communication chain management, as outlined here.
More info >>

 
Industry Events

BioTrinity 2019

30 April - 1 May 2019, etc.venues 155 Bishopsgate, London EC2M 3YD

BioTrinity 2019 is taking place from the 30th April – 1stMay at etc.venues 155 Bishopsgatein London. Now in its 13th year, BioTrinity remains the leading Life Sciences Biopartnering and Investment conference in Europe, and generates unrivalled opportunities for life science companies, academics, investors, and major pharmaceutical players to come together to do deals and establish collaborations.
More info >>

 

 

©2000-2011 Samedan Ltd.
Add to favourites

Print this page

Send to a friend
Privacy statement