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Smart Breath-Actuated Mesh Nebulisers for Combination Products

As in several other industries, the Internet of Things (IoT) has also found its place in the medical industry. The medical IoT with connectivity functions offers the opportunity to improve patient adherence. In the respiratory field, more specifically in inhalation therapy, this constitutes a major contribution. Low adherence can be observed in different types of treatment, as patients may not always comply with their prescription. However, in inhalation therapy, this is further attenuated by the potential mishandling of devices, which results in even lower levels of adherence (1).

Smart devices arise as a solution that supports the monitoring and tracking of treatment, educating and encouraging patients to adhere to their treatment and benefit from it.

These smart solutions can be presented as either add-ons (e.g., smart caps) or be incorporated within the nebulisers. Bluetooth has become one of the top choices for the connectivity environment that links smart nebulisers to mobile devices. Some of the main functions include storage of treatment information, alarm reminders, test evaluations, and educational materials (2).

Breath-actuation technology is another main feature encountered in innovative mesh nebulisers. It consists of a mechanism that triggers aerosol generation during a specific period of the inhalation phase only. The idea behind this function is to reduce the amount of aerosol that is otherwise emitted directly into the environment, and to enhance drug delivery efficiency (3). By combining hardware and software, it is possible to activate the aerosolisation of liquid formulations during the most optimal intervals of the breathing pattern, which, besides improving the delivered dose, also helps in the reduction of fugitive aerosol emission, which may be hazardous to those around patients receiving their inhalation treatment (4).

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Hernan Cuevas Brun is the Marketing Manager at HCmed Innovations. He is responsible for the marketing analysis and research of new products, as well as the branding of HCmed’s commercially available mesh nebulisers. He is involved in the development of connected devices, supporting the programmes by researching and establishing alliances with new partners. Hernan has more than six years of experience in the drug delivery field, holding a degree in Biomedical Engineering and an MBA. He is in charge of coordinating HCmed’s participation and publications in major conferences such as the European Respiratory Society International Congress and the American Thoracic Society Conference.
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Hernan Cuevas Brun
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