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Pharmaceutical Manufacturing and Packing Sourcer

pmps
Winter 2005
At the cutting edge of the latest industry developments, Samedan is adept at keeping the information you need at your fingertips. PMPS provides a unique platform of communication for the market across Europe, North America and the rest of the developed world. To find out what's hot in the world of pharmaceuticals, take a look below at the range of articles featured in this issue of PMPS
   
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Manufacturing
Although not without its problems, biotech is working towards overcoming the initial dilemmas that first presented themselves with its conception in the 1970s. Stephanie Finnegan at Goodwin Biotech provides us with a brief history in Thirty Years of Highs and Lows  
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In Manufacturing a New Era in Stainless Steel Tubing, Ernest A Benway at Swagelok Company recounts how the new ASME-BPE standard's use in the industry has expanded on a worldwide basis, and shows how this relates to the selection of automatic welding systems  
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In Having Designs on Tried and Tested Sampling Techniques, Rene van der Gaag of Tyco Valves and Controls presents the progressive approaches to modern sampling requirements  
Viable microbiological environmental monitoring is a key aspect of any sterility assurance programme. In Active Air-Sampling - The Selection Process Made Easy, Tim Sandle at Bio Products Laboratory tells us why  
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Packaging, Packing & Anti-Counterfeiting
In Recognising the Benefits of Automatic Identification, Charlie Plain-Jones at Absolute Vision Ltd demonstrates how automatic identification can assist in creating a proficient manufacturing environment  
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In Packaging and Herbal Medicine: Are You Compliant?, Professor Elizabeth Williamson at Reading University depicts the numerous concerns that must be accounted for in the design and production of herbal medicines  
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Machine vision has evolved to become a popular tool in the packing, packaging and labelling industry. In Envisioning Quality Packaging, Leigh Simpson at Cognex UK Ltd sets out the varied accomplishments that are making it an ideal choice  
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Formulations, Ingredients and Excipients
Recent efforts in drug development have taken biopharmaceuticals, such as peptides, into account, as well as encompassing the classical small-molecule concept. Juergen Hess and Christian Reiser at responsif GmbH provide a summary of these breakthroughs, in An Overview of the Advanced Delivery of Macromolecules  
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In Looking to the Future: One Company to Meet all your Disposable Contained Transfer Technology Needs, PMPS talks to Rutger Vandiest at ATMI LifeSciences about the company's latest developments and future aims  
The problem of polymorphism is nothing new in the pharmaceutical industry, especially since high profile incidences like Abbott's Norvir®. Dr Lyn Hughes at Rohm and Haas heralds an unprecedented approach to overcoming this, in Shedding New Light on an Old Problem  
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Dosage Forms
In Gaining the Edge in an Increasingly Challenging Injectables Market, Dr Kevin Maynard at Imprint Pharmaceuticals Ltd focuses on the conflicting dilemmas surrounding the successful marketing of injectable therapeutics - that is, patient recovery and means of delivery - in the spotlight  
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In Weighing it Up, Alan Homes at Raupack charts innovations in full nett weight control in capsules, illuminating past mistakes that have concentrated on the gross weight of the hard gelatine capsule instead of the product inside  
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Nasal and Pulmonary Drug Delivery
In spite of chronic lung disease accounting for 5,000 deaths each year in the US alone, inadequate patient education programmes and commitment to administering treatment effectively still exist. In Running on Empty, Treasa Devine at Bang & Olufsen Medicom explains how new single increment dose counters on inhaler devices may help to overcome the poor management of respiratory diseases  
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In An Ideal Delivery Route, Jeremy Southall at Bespak Europe concludes an investigation which was first featured in PMPS Summer 2005. In this second instalment, the development of air-stream technology to target specific tissues in the nose is put under the microscope  
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Chronic obstructive pulmonary disease, currently accounts for 17.4 per cent of deaths worldwide. In COPD: Putting out a Fire, Dr Faiz Kermani at Chiltern reviews the efforts to avert a potential health disaster  
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Drug Delivery
Peter Wirz at Christ tells us how ozone can provide the required purified water systems against microbiological contamination, in Pure and Simple  
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In Easy to Swallow: Is this the End of the Age of Bitter Pills?, Dr Ina Schicker at the European Sensory Network illustrates the advantages of using sensory product optimisation to ensure more efficient drug delivery and therefore better patient compliance  
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Anti-Counterfeiting
In Making a Good First Impression, Rick Kettinger at Colorcon demonstrates how branding is being utilised to engage with consumers by distinguishing tablets, thus establishing a product in the marketplace  
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Incidences of counterfeiting continue to jeopardise the safe delivery of drugs to patients. In Optical Safety Features for Blisterpacks, Josef Kothmeier of Perlen outlines how widely-used push-through blisterpacks can be effective in providing protection against tampering.  
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Edward A Madden and Edward J Kelly at Tilleke & Gibbins International Ltd detail the significance of IP laws, and how the West has been at the forefront in this and related issues, in East Versus West: IP, Thailand and the Western World  
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The issue of counterfeiting is being tackled in a more well rounded way, taking into consideration all possible avenues for foul play, starting with the supply chain. Brenda Kelly at SupplyScape presents a new safe and secure supply chain model, in Chain Reaction  
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Clinical Trial Management
Automated label verification technology in clinical trial supplies is contributing to a more efficient route to market for drugs against the backdrop of increased red tape, contends Derek McKay at Clinical Trial Services, in Putting a Label on Clinical Trial Success  
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Innovations in electronic data recording technology are providing new ways to collect, store and retrieve process data, making them more accessible to a range of applications. Martin Binney at ABB illustrates how in A New Era in Data Recording

 
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IT and Logistics
PMPS provides exclusive coverage of the most recent update to the World Health Organization's International Packaging and Shipping of Vaccines in Navigating a Regulatory Minefield  
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In Shipping in Change, Dr Umit Kartoglu at the World Health Organization summarises these latest developments of one of the most widely used manuals in the field of immunisation  
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Overcoming all the demands on the supply chain can be challenging. In Optimising a Pressurised Supply Chain, Simon Shorthose at IBS UK Ltd declares that software can help this process become more efficient in, for example, coping with the volume of transactions  
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The long-winded process of getting medication from manufacturer to the patient is complicated if the medication is temperature-sensitive. In Overcoming the Weakest Link, Chris Meyer at Acutemp reviews the latest applications that aim to make the cold chain more effective  
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Previews
Have you got your ticket for Bio/PharMOS and Bio/PharDOS, taking place in Monaco this March? In The Essence of Today's Life Science Industry, Dr Patricia Lobo gives us the lowdown on this year's event  
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Edited by
Dr Graham Hughes
Consultant in
Pharmaceutical
Development
Published quarterly in
February, May,
August and November

News and Press Releases

Medical Tourism Amongst Key Factors Driving Huge Growth in Malaysian Healthcare Market by 2020, says GlobalData

LONDON, UK (GlobalData), 23 July 2014 - Medical tourism, easy regulatory guidelines, a lack of strict price regulation and an increasing elderly population will be the main contributors to the rapid rise in Malaysia’s healthcare market value by 2020, according to research and consulting firm GlobalData.
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White Papers

Medpace Reference Laboratories establishes state of the art Flow Cytometry techniques for flexible approaches to clinical trials across multiple therapeutic areas.

Medpace

Cytometry is the process of measuring the properties of individual cells. These properties may include gene or protein expression, chemical properties, deoxyribonucleic acid (DNA) content, and various cellular functions. The earliest methods of cytometry relied upon light microscopy for the classification and observation of cells and cellular components. Microscopy permitted direct visual observation of cells for the first time, leading to the classification of cells by morphology and insight into cellular functions. However, the time required for microscopic analysis constrains the number of samples or number of cells in each sample that can be examined. Therefore, the utility of microscopy for analysis of rare cells or in situations where sample throughput is a priority is limited. Flow cytometry was developed largely to improve upon these limitations.
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Industry Events

Cancer Vaccines

15-16 September 2014, Holiday Inn Regents Park, London UK

The global therapeutic cancer vaccines market is expected to grow to a value of $7.8 billion by 2019. As companies look to develop new drugs to enter this rapidly growing industry, Cancer Vaccines 2014 will mark the path forward in terms of cancer vaccine research, clinical development and regulation.
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