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PUBLICATIONS

Pharmaceutical Manufacturing and Packing Sourcer

pmps
Spring 2004
At the cutting edge of the latest industry developments, Samedan is adept at keeping the information you need at your fingertips. PMPS provides a unique platform of communication for the market across Europe, North America and the rest of the developed world. To find out what's hot in the world of pharmaceuticals, take a look below at the range of articles featured in this issue of PMPS
   
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In her Editor's Letter, Dr Patricia Lobo reviews the articles in this issue of PMPS  
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Formulations, Ingredients and Excipients
There has been a substantial increase in the sales volume for chiral technologies - Dr Thomas C Rosen and Dr Thomas Daußmann at Jülich Fine Chemicals, examine this growth area in Chiral Building Blocks via Biocatalytic Methods  
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Dr Paul Smith, Technical Manager at Sensient Pharmaceutical Technologies, outlines the vital role played by colourants in The Colouration of Solid Oral Dosage Forms  
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SOLID DOSAGE
Taste masking can be fundamental to patient compliance. Dr Lyn Hughes, Global Technical Service Manager for Healthcare at Rohm and Hass, looks at the science and rationale behind Making Medicines Taste Better  
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Henrik Schwartzbach, Pharma Division Process Technologist at Niro A/S, details ways to Achieve Controlled Release and Increased Bioavailability of Pharmaceutical Compounds Through Spray Drying  
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STERILE MANUFACTURING
Phil Plummer, Sales Director at Ingredient Handling Solutions Ltd, discusses The Importance of Automated Ingredients Handling when using Minor Ingredients in Pharmaceutical Production  
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Dr Wolfgang Preibsch, European Marketing Manager, Pharmacos Division at Ecolab GmbH & Co OHG, gives us the lowdown on aqueous cleaning solutions for the pharmaceutical industry in Cleaning Validation: Why do Cleaners Work?  
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CONTRACT MANUFACTURING
Outsourced Manufacturing in Life Science: A Modern Industrial Revolution? Charles Horth, Life Science Consulting Editor for Cytops, guides us through the potential answers  
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Looking to improve pharmaceutical manufacturing and packing processes? Daniel Nash, Manufacturing Advisor at London Manufacturing Advisory Service, looks at Eliminating Waste and Adding Value  
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Planning and Optimisation Software Facilitates Production Planning of Ingredients - find out how with Dr -Ing Christoph Plapp, CEO at Axxom Software  
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In Magnetic Resonance Check-Weighing, Valerie Scott, Senior Consultant at Generics asks whether this new technology the key to performance improvements in pharmaceutical manufacturing?  
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Irwin Hodgkiss of Burkert Fluid Control Systems, takes an indepth look at The Growth of Fieldbus in the Process Industry  
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Drug Delivery
The concept of drug delivery is evolving - in some cases, delivery technologies are even essential to a drug product's very success. In New Drug Delivery Strategies Offer Opportunities for Improved Drug Performance and Expanded Markets, Dr Christopher Searcy, Vice President, Corporate Development at Nektar Therapeutics, looks at a changing industry  
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njThe use of skin as an alternative route of delivering medicaments has been relatively slow. But this under-utilised area is fast becoming a hot topic, as Dr Marc B Brown, Chief Technical Officer and Franklin K Akomeah, Research Scientist at MedPharm Ltd, explain in New Developments in Transdermal Drug Delivery Systems  
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Mel Snyder, Vice President of Market Development and Thomas CK Chan, Vice President of Research and Development and Chief Technology Officer of MacroChem Corporation, make the case for Absorption-Enhanced Topical Medication: Opportunity for New Speciality Pharmaceuticals  
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From a marketing point of view, injectable therapeutics pose a challenge. In Injectables and the Competitive Edge, Dr Kevin Maynard, Business Development Director at Imprint Pharmaceuticals Ltd, examines the conflicts and potential resolutions  
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In Dynamic Modelling and Simulation for Nasal Drug Delivery, Dr Jin Yan, Dr Atul Karanjkar and Martin Branagan, Healthcare Team at Fluent Europe Ltd, present a study using computational fluid dynamics simulation technology  
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Dr Jürgen Hess, Head of Scientific Affairs, and Dr Christian Reiser, Managing Director at responsif GmbH, look to Novel Approaches Towards Cancer Therapy: Modified Concept for Autologous Tumour Cell Vaccination and Capsoid-Based Delivery of Tumour Antigens  
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Packing, Packaging and Labelling
Olivier Leprince, Plant Manager, and Hans Peter Manser, Marketing and Sales Manager at SCHOTT, lead us through the Challenges and Trends of Primary Packaging Solutions  
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What can modern robotic systems offer today's pharmaceutical packaging industry? Your questions answered in The Case for Robotics in Pharmaceutical Packaging Lines by Frank-Peter Kirgis, Product Manager of SIG Delta Robots at SIG Pack Systems  
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Clever Coding Meets the Pharma Challenge - find out how with Charles Randon, Senior Product Manager at Linx Printing Technologies  
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Thomas Voelcker, Managing Director of the ProSecure Unit at Schreiner, charts the progress of Innovative Tampering Protection for the Pharmaceutical Industry  
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Anti-Counterfeiting
Andrew Rink, Marketing Manager for Product Security at Flex Products, reviews Overt Anticounterfeit Protection for Pharmaceutical Drugs  
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John Allan, Director of the Pharmaceutical Investigation Division at Carratu International Plc, looks at the latest intelligence in Pharmaceutical Counterfeiting ° Predicting the Future  
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Clinical Trial Supplies
Marty Boom, Senior Managing Consultant, and Eugène van Dijk, Senior Consultant at World Class International, look at proven techniques which equip clinical supplies units to cope with today's extreme pressures in From Cottage Industry to Supply Chain Process  
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In Assessing the Implications of the New Drug Labelling Legislation, Dr Sue Miles, Head of Clinical Trials Services at Brecon Pharmaceuticals Ltd, considers the implications of legislation on the assembly and packaging of pharmaceutical products  
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The US FDA wants to use 'track and trace' technology to secure the integrity of the drug supply chain, Alaster Purchase, Health Care Project Manager at e.centre, looks at Getting RFID into Health Care  
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Chris Tierney, Clinical Trials Development Manager of Exel's Health Care Sector, gives an indepth review of Clinical Trials Logistics ° Creating Value in the Clinical Supplies Chain  
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LOGISTICS
Revolutionary materials, new style shippers and self-help opportunities via the web ° Katrina Bray, Marketing Manager at Laminar Medica, explains How New Materials and Technologies are putting Validated Shipping within Reach of Everyone  
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Peter Jones, Head of Mu Solutions at Hitachi, examines the use of RFID tags in Building a Healthier System: Improving Efficiency and Safety in the Pharmaceutical Supply Chain  
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Natalie Roy, Product Manager, and James Wilson, Technical Director at Gemini Data Loggers (UK) Ltd, consider the benefits of Using Technological Advances to Simplify Cold Chain Monitoring Procedures  
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Consultant Editor
Bruce Horton,
Partner in charge of
Accenture’s European
Health & Life Sciences
Supply Chain
Published quarterly in
February, May,
August and November

Industry Events

4th Annual Patient Recruitment and Retention in Clinical Trials

13-15 October 2008, Amsterdam

Patient recruitment is now consuming thirty percent of clinical trial time - more time than any other clinical trial activity - and almost half of all trial delays result from patient recruitment problems. As the recruiting culture becomes more sophisticated and the forces affecting patient enrollment grow more numerous and complex, pharmaceutical companies are striving to discover new strategies to facilitate enrollment in clinical trials. With increasing industry pressure to develop, test and market greater numbers of new drugs faster, pharmaceutical companies need to perform clinical trials as quickly as possible. Inefficient patient recruitment processes is a formidable barrier to pharmaceutical companies' success in launching new products. Improving the patient recruitment process is imperative to avoid wasted investments and eliminate costly delays in bringing new drugs to market -- today and even more so in the not-so-distant future. Improved patient recruitment presents one of the largest opportunities for pharmaceutical companies to eliminate delays in clinical trials, thereby making it possible to reduce time to market.  With patent time limits and large overheads meaning that any delays in the development timeline can be disastrous, a good understanding of how to successfully recruit patients for trials is vital for any company looking to succeed.
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News and Press Releases

PFIZER PRESENTS OVERALL SURVIVAL DATA FOR SUTENT™ VERSUS INTERFERON-ALFA

Chicago, 31 May 2008- Results from a landmark study have shown that sunitinib (SUTENT™) has demonstrated overall survival greater than two years in patients with metastatic renal cell carcinoma (mRCC), also known as advanced kidney cancer.  This is the first time overall survival data representing more than two years has been achieved in the first line setting of mRCC, which is clinically meaningful and reflective of major advances in the treatment of kidney cancer. 
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