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Pharmaceutical Manufacturing and Packing Sourcer

Cleaning Validation: Why do Cleaners Work?

Aqueous Cleaning Solutions for the Pharmaceutical Industry

Different types of cleaners are used in the pharmaceutical industry, these include: organic solvents, bulk chemicals such as caustic, and formulated specialist detergents (aqueous). This article will focus on aqueous detergents, their components and the way they work.

In general, 'solvents' are used to remove residues from production equipment to avoid carry-over into the following batches. Solvents may be organic, like acetone, alcohols and so on, or water. As a booster for this solvent, bulk chemicals such as caustic are used, or specially designed detergents and additives, which increase the potency of water to dissolve residues to the maximum. To reach the maximum cleaning and sanitation efficiency, four factors must be taken into account

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By Dr Wolfgang Preibsch, European Marketing Manager, Pharmacos Division at Ecolab GmbH & Co OHG

Dr Wolfgang Preibsch is the European Marketing Manager for the Pharmacos Division at Ecolab, in Duesseldorf, which is the European headquarters. He gained his PhD in Chemistry from the University of Hannover. Since 1979, he has held a variety of positions in R&D with responsibility for the development of cleaners for industrial use, with particular focus on cleaners for automated cleaning systems (CIP). In 1992, he joined Ecolab in a similar capacity, before moving to marketing in 1995.
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Dr Wolfgang Preibsch
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