|
 |
Pharmaceutical Manufacturing and Packing Sourcer
|
The manufacturing area of semi-finished products to produce suppositories is divided into two main plants. These two plants have similar operating modes, except for the capacity of the melting and preparation vessels, which is 1000lt and 600lt in plants one and two, respectively. In turn, each plant is made up of vessels with the same capacity, in particular:
One melting vessel, which is only used to melt the fatty base and other excipients, wherever applicable in the corresponding formulation
Two preparing vessels, in which the melted mass is added with the integration of the active ingredients in the form of powder, solution or preconcentrated suspension according to the amounts and manufacturing method being used
This layout allows processing to take place in three continuous shifts, thus guaranteeing feeding of the packaging lines from the first preparing vessel while the mass, which will be used to manufacture the following product batch, is being melted in the melting vessel. During this time, the second preparing vessel, into which the melted mass will be poured and added with the active ingredient, is cleaned and dried.
Melting, cleaning, batch preparation and the capacity of the packaging lines have been conceived so as to guarantee consistency of the above-cited manufacturing flowchart with economic batches, which require about one shift on average. However, the plant can also manage larger batches.
|
Read full article >>
|
|
 |
|
| Rate this article |
You must be a member of the site to make a vote. |
|
Average rating: |
0 |
| | | | | |
|
|
 |
Industry Events |
 |
Small Scale Biomanufacturing – clinical trials, cell & gene therapies
18 September 2008, Clifton Pavilion, Bristol Zoo Gardens, Bristol
This one day conference, sponsored by bioProcessUK and organised by BioApproaches South West, will cover key, important topics relating to small scale GMP biomanufacturing.
More info >> |
|
 |
News and Press Releases |
 |
Ultra slim and ultra quick
More info >>
|
|
 |
