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In Sailing to Utopia: A Revolutionary New Phase for the Pharmaceutical Cold Chain Shipping Scene

New materials are currently being introduced that will radically improve the design efficiency of contemporary validated temperature controlled shippers for pharmaceutical products. They will also have the potential to extend the principle of validated shipping to product types hitherto excluded, particularly those that require warm as opposed to chilled or frozen shipping solutions.

This article will discuss these new materials including the applications for which they are suitable, and their various advantages and disadvantages. The new generation of materials all have one thing in common: they are phase change materials or PCMs. As most readers will appreciate, there is no secret about PCMs: in fact anybody who is using temperature-controlled packaging (TCP) is already used to the concept - dry ice, 00C water-based gel or cool packs all qualify.

This is because PCMs are simply materials that absorb or release large amounts of heat energy whilst changing phase - latent heat capacity. This happens when solids turn to liquids, liquids turn to solids or some other similar phase change happens. As water absorbs and releases a comparatively large amount of latent heat energy, it raises no safety issues in respect of either transportation or disposal and is widely available. It also makes an excellent material for the purpose of keeping products at chilled temperatures. Indeed, 00C water-based materials in the form of gel-packs or cool-packs are widely used as PCMs in +20C to +80C shippers. This is the temperature range for most pharmaceutical products that require cold chain distribution.


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By Geraint Thomas, Technical Director at Laminar Medica

Geraint Thomas graduated from Brunel University in 1996 with a first in Industrial Product Design. After working as a Board Game Engineer for Hasbro toys, he joined Laminar Medica in 1998 as a Packaging Development Technologist with responsibility for packaging solutions and validation packages for validated insulated shipper design. Now working as Technical Director, Geraint has been instrumental in realising Laminar Medica's development programme, including the expansion of the company's validation laboratory.

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