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home > pmps > spring 2003 > controlled delivery technology in nutraceutical applications: a user's perspective
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Pharmaceutical Manufacturing and Packing Sourcer

Controlled Delivery Technology in Nutraceutical Applications: A User's Perspective

Dietary supplements are now widely used by consumers to complement a healthy balanced diet. However, in a highly competitive marketplace, key points of differentiation can be obtained by using the latest technology to produce ingredients that offer consumers dietary supplements that have improved efficiency and convenience. One of the most exciting recent developments in dietary supplement ingredient manufacture is controlled delivery technology or CDTTM. Materials science, colloid chemistry and biopharmaceutics have been applied to develop monolithic matrix systems collectively referred to as 'self-correcting matrix delivery systems'. These systems control the release of a precise quantity of active ingredient over a pre-determined timeframe. In this article, we review the science behind CDT, discuss its comparative benefits and highlight how this technology has been successfully applied.

What is Controlled Release Technology?

A platform of patented technologies has been developed that can be applied to compounds with a wide range of properties and characteristics. CDT is based upon a simple hydrophilic swellable matrix model, but it incorporates a number of geometrical modifications. It uses in situ ionic associations between the active compound and the ionic excipients to control the diffusion of a precise quantity of either single or multiple active ingredients from the supplement product over a predetermined time period.


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By Dr Michelle Jones, Technical Manager Europe at ADM Natural Health and Nutrition, in association with SCOLR® Inc.

Dr Michelle Jones is Technical Manager for Europe with ADM's Natural Health and Nutrition division. A PhD Chemist, Dr Jones joined ADM with a wealth of nutritional and technical experience gained from technical management positions and involvement with a key food industry trade association focusing on health and nutrition. In her current role she provides scientific guidance and service in this growth area of functional ingredients.

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Dr Michelle Jones
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