spacer
home > pmps > winter 2002 > starch based excipients for tabletting
PUBLICATIONS
Pharmaceutical Manufacturing and Packing Sourcer

Starch Based Excipients for Tabletting

Excipients are commonly defined as the additives used to convert pharmacologically active compounds into a pharmaceutical dosage form suitable for administering to patients. They are useful both as diluent of the active drug and processing aid for the formulation. Excipients should be physiologically inert and compatible with active ingredients. They should show no ageing in terms of physical and chemical stability and should be neutral in terms of odour, taste and colour. Many natural carbohydrates and their derivatives meet these requirements and therefore are widely used in the pharmaceutical industry.

Wet and dry granulation are frequently used methods for the manufacturing of tablets. But with the availability of specific developed excipients the pharmaceutical industry has the opportunity to choose a more efficient and economical process: direct compression. The choice of excipient is extremely critical in formulating direct compression tablets. Longstanding suppliers of pharmaceutical excipients, are therefore proactive in the research and development of new forms of excipient that are suitable for direct compression.


Read full article from PDF >>

Rate this article You must be a member of the site to make a vote.  
Average rating:
0
     

There are no comments in regards to this article.

spacer
By Dr Jacques Michaud, Business Manager Pharma & Cosmetics at Cerestar, Belgium
Dr Jacques Michaud obtained a PhD in Organic Chemistry in 1990 from the Universitй Pierre et Marie Curie, Paris VI. Dr Michaud has been working for Cerestar since 1990 where he managed the Application Centre Pharma & Chemical in the R&D centre of Cerestar in Vilvoorde, Belgium. The centre is in charge of developing new applications of starch and starch derivatives for the chemical and the pharmaceutical industries.

Dr Michaud is an expert at the European Pharmacopoeia and represents his company at the IPEC. He has been recently appointed Business Manager, and is responsible for co-ordinating the technical and commercial activities of Cerestar in the pharmaceutical and cosmetics applications.

spacer
Dr Jacques Michaud
spacer
spacer
Print this page
Send to a friend
Privacy statement
News and Press Releases

CPI to showcase results from BioStreamline project developing novel biotherapeutics

CPI, a UK-based technology innovation centre and a founding member of the High Value Manufacturing Catapult, announced today that it will host an event in Darlington, UK on 26 June 2019 to disseminate the results of the £11.2M BioStreamline project to optimise the development of novel therapeutics. During the event, the project partners — Lonza Biologics, UCB Celltech, Sphere Fluidics, Horizon Discovery Group plc (Horizon), Alcyomics Ltd and CPI — will showcase the results and discuss the potential impact on overcoming some of the most significant shortcomings of the biologics supply chain.
More info >>

White Papers

Recommendations for Implementing Assessment Criteria Guidelines in Lymphoma and Chronic Lymphocytic Leukemia Clinical Trials

Perceptive Informatics

Standardized assessment criteria are becoming increasingly important in obtaining valid outcomes in oncology clinical trials. While standardized criteria encourage a more uniform approach to assessing clinical trial data, they are often subject to the interpretation of the user. These differences in interpretation, while seemingly minor, can have a major impact on assessments. The most commonly used standardized criteria for lymphoma have been no exception. Differences such as minimum new lesion size, lymph node normalization size requirements, inclusion of extranodal lesions and assessment of organomegaly can have a profound effect on overall response. Additionally, heightened scrutiny of the assessment criteria used in a given protocol can lead to questions about a drug’s efficacy if not applied correctly according to regulators’ interpretation.
More info >>

 
Industry Events

SAPHEX 2019

23-24 October 2019, GALLAGHER CONVENTION CENTRE, 10 RICHARDS DRIVE, HALFWAY HOUSE, MIDRAND, 1685, SOUTH AFRICA

SAPHEX 2019 will be held on the 23rd-24th October at the Gallagher Convention Centre, Johannesburg, South Africa.
More info >>

 

 

©2000-2011 Samedan Ltd.
Add to favourites

Print this page

Send to a friend
Privacy statement