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Pharmaceutical Manufacturing and Packing Sourcer

Uncontrolled Growth of Controlled Release Drug Delivery Technology and Markets

Controlled drug delivery is a widely recognised high-growth sector within the US$300 billion pharmaceutical market (1). Controlled drug delivery systems are formulations, devices, and techniques designed to deliver therapeutic agents to targeted physiology and to provide efficacious release of agents. The systems on their own are not therapies, but improve the efficacy and/or safety of the drugs they carry. How a drug is delivered to the body is almost as important as the drug itself, yet drug delivery technology accounts for only 14 per cent of the pharmaceutical market. Fortunately, advanced drug delivery technologies, including controlled release technologies, are experiencing double digit growth and are expected to account for US$7 billion of the market by 2005 (2).Controlled release drug delivery technologies are expanding exponentially with applications in every imaginable route of administration because of the indisputable therapeutic benefit this delivery technology brings.


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By Joe McDonough and Wade Schlameus, Pharmaceutical Research and Microencapsulation Specialists at the Southwest Research Institute

Dr Joe McDonough is a Senior Research Scientist specialising in pharmaceutical research at the Southwest Research InstituteTM (SwRI®) Microencapsulation, Nanomaterials, and Process Engineering Department. Dr McDonough holds a Bachelor's Degree in Chemistry from the University of Dallas and a Doctorate in Organic Chemistry from Texas Tech University.

He joined the SwRI staff in 2000 with 10 years' experience in pharmaceutical development, manufacturing, regulatory compliance and licensing at Hoechst Celanese and Ilex Oncology, Inc. He holds eight patents and has authored or co-authored more than 10 articles in pharmaceutical development.

H. Wade Schlameus is Manager of the Microencapsulation and Controlled Release Section at Southwest Research InstituteTM (SwRI®). Mr Schlameus has a Bachelor's Degree in Chemistry from Southwest Texas State University and more than 40 years' experience in encapsulation technology at SwRI.

He specialises in developing controlled release formulations of pharmaceuticals, biological organisms, foods, agricultural products, consumer products and industrial chemicals. He holds 10 patents and is co-author of more than 25 technical publications and presentations associated with microencapsulation technology.


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Dr Joe McDonough
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H. Wade Schlameus
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