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Pharmaceutical Manufacturing and Packing Sourcer

Improving Laboratory Containment by a Factor of 10

High potency compounds in the form of active pharmaceutical ingredients (APIs) or highly active pharmaceutical ingredients (HAPIs) are a growing source of concern in today's pharmaceutical industry. In 1990 only around 5 per cent of materials passing through drug development necessitated special containment measures. However, in 2001 at least 35 per cent of compounds meet these criteria.

Many health and safety professionals and facility managers are considering how to provide effective containment and this paper sets out to demonstrate that a number of effective solutions do exist, without having to resort to the unpopular personal protection equipment and air suit methods of operator protection. The problem is how to improve laboratory containment by a factor of 10. For many pharmaceutical research facilities facing the increased use of potent compounds or materials with an undocumented toxicity, guaranteeing a safe workplace is posing serious problems. With hazards approaching the microgram level, how can effective hazard containment for technicians and scientists working in the laboratory environment be assured?


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By Martyn Ryder, Managing Director of Extract Technology, Part of the Carlisle Life Sciences Group
Martyn Ryder is the Managing Director of Extract Technology, part of the Carlisle Life Science Group. He was educated at Leeds Polytechnic in HVAC and Building Services.

In 1981 he founded Extract Technology, a supplier of pharmaceutical dust control and high containment systems, based in Huddersfield, UK.

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Martyn Ryder
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