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Pharmaceutical Manufacturing and Packing Sourcer

Pharmaceutical Water Storageand Distribution Design

Pharmaceutical water systems provide a vital service to any pharmaceutical manufacturing facility. The key concept of pharmaceutical water storage and distribution design is to ensure that the system does not significantly deteriorate the quality of supplied process water. The system may incorporate process changes, such as temperature and pressure, to suit the end user's requirements, but the overriding factor is to deliver water within the correct validated specifications required for the application.

The major design considerations for pharmaceutical water storage and distribution systems are the quantity and quality of water required, along with the system's installation and operating costs. To maintain water quality, the storage and distribution system should be designed to inhibit microbial growth and to minimise any outside contamination of the circulating water. The fundamental points that help meet such requirements include:


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By David Forte, Process Engineer at the Water Group, Pharmatec Procip Ltd, UK

David Forte graduated from the University of Wales with an MEng (Hons) in Chemical Engineering. Whilst studying, he spent time on industrial placements with Dow Corning (South Wales) and Agip (Italy). David joined Pharmatec Procip soon after qualifying and has very quickly established himself as one of the leading process engineers within the organisation, with specialist expertise in the design of critical pure water systems. He has been responsible for the design of water systems supplied and installed within AstraZeneca, Rhodia-Chirex, GlaxoSmithKline and Boots PLC amongst others. David often presents talks at industrial seminars, including the Parenteral Society.

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David Forte
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Industry Events

4th Annual Patient Recruitment and Retention in Clinical Trials

13-15 October 2008, Amsterdam

Patient recruitment is now consuming thirty percent of clinical trial time - more time than any other clinical trial activity - and almost half of all trial delays result from patient recruitment problems. As the recruiting culture becomes more sophisticated and the forces affecting patient enrollment grow more numerous and complex, pharmaceutical companies are striving to discover new strategies to facilitate enrollment in clinical trials. With increasing industry pressure to develop, test and market greater numbers of new drugs faster, pharmaceutical companies need to perform clinical trials as quickly as possible. Inefficient patient recruitment processes is a formidable barrier to pharmaceutical companies' success in launching new products. Improving the patient recruitment process is imperative to avoid wasted investments and eliminate costly delays in bringing new drugs to market -- today and even more so in the not-so-distant future. Improved patient recruitment presents one of the largest opportunities for pharmaceutical companies to eliminate delays in clinical trials, thereby making it possible to reduce time to market.  With patent time limits and large overheads meaning that any delays in the development timeline can be disastrous, a good understanding of how to successfully recruit patients for trials is vital for any company looking to succeed.
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