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home > pmps > autumn 2001 > an introduction to transdermal drug delivery systems

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Pharmaceutical Manufacturing and Packing Sourcer An Introduction to Transdermal Drug Delivery Systems
This is a two-part article dealing with the basic structure and production of transdermal drug delivery systems (TDDS). Today, this system represents one of the most sophisticated drug delivery technologies, helping to administer active pharmaceutical ingredients in lower doses and thereby achieving more stable blood levels. Additionally, the administration of TDDS need not be repeated often, therefore encouraging patient compliance, while at the same time resulting in fewer side effects. In the first part of this article, the structures and components of the most common TDDS will be presented. In the second part, the manufacturing process will be discussed, along with the problems and remedies of the most popular type of TDDS - the matrix TDDS, or matrix patches.
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By Spyridon A. Fotinos, Executive Vice President - Corporate
Research & Innovation, at Lavipharm Group of Companies

Spyridon Fotinos studied pharmaceutics at the University of Athens, before going on to study chemistry at the University of Thessaloniki. He joined Lavipharm in 1979, and in 1987,established the Research and Development Department, of which he has since been a Director. Spyridon's current position is Executive Vice President - Corporate Research and Innovation. Prior to his time at Lavipharm, he served for four years as Director of Planning and Studies at Minerva Pharmaceuticals.
Spyridon is a patent holder in the areas of pharmaceutical and cosmetic delivery technology, antioxidant and enzymic systems, and he is a member of several Greek and international scientific organisations.