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Pharmaceutical Manufacturing and Packing Sourcer

pmps
Spring 2007
At the cutting edge of the latest industry developments, Samedan is adept at keeping the information you need at your fingertips. PMPS provides a unique platform of communication for the market across Europe, North America and the rest of the developed world. To find out what's hot in the world of pharmaceuticals, take a look below at the range of articles featured in this issue of PMPS.
   
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Manufacturing
The supply chain is riddled with risks and potential disasters. Investigating every possible incident is the best way of Controlling the Contaminants, advises Chris Landeg at RSSL Pharma  
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Lyophilisation Closures are numerous, and not one fits the needs of all applications. Compendial, functional and stability tests are crucial for any drug contact product and, argues Douglas Cusato at Helvoet Pharma, there shouldn’t be an exception for lyophilisation  
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Richard Shannon of Almac Clinical Services explains how the challenges posed by over-encapsulation are surmountable and, once defeated, ensure accuracy and integrity in study results, in Unmasking the Blind of Over-Encapsulation  
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Aseptic techniques are being relied upon more and more by pharmaceutical companies to ensure the sterility of products. Colin Booth at Oxoid Limited addresses the relationship between control measures, in Clean and in Control  
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Innovation in a Bigger Box is the recipe for success, according to PA Consulting Group’s Paul Earnshaw. He suggests widening the horizons of technologies and processes in manufacturing for commercial results  
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Hugh Lloyd of ABB Limited endorses raw conductivity measurements in determining contaminant control to improve water quality, as well as the reliability of tests, in Bringing Contaminant Control In-Line  
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Packaging, Packing & Anti-Counterfeiting
Stick to What You Know, recommends Holger Botsch at Sigpack; stick packs are a versatile, inexpensive and convenient packaging solution – that are ideal for the pharmaceutical industry  
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Change control and audit trailing can have a considerable impact on compliance and efficiency, state Chiara Grimaldi and Stefan Harwart of BearingPoint, in Taking Control of Change in Artwork and Labelling  
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The Other Drug Problem, contends Tassilo Korab of HCPC, is the strikingly low level of patient compliance. Effective packaging can play a fundamental role in the solution of this crises  
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Peter Tindale at Pillar Technologies illustrates the necessary factors of a successful induction seal, and its advantages over its competitors, in Lifting the Lid on Induction Sealing  
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In 14 months, all patient information leaflets are to comply with a new EC directive, Sophie Hobson at TRAC Services outlines the cost and time implications, in Readability Testing – A Bitter ‘Pil’ to Swallow?  
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Formulations, Ingredients and Excipients
Innovation in Excipients is the best solution for pharmaceutical progress, review Bodo Fritzsching, Maj-Britt Babbel and Oliver Luhn from Palatinit GmbH as they examine a newly developed isomalt excipient  
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Major changes in the pharmaceutical excipient market result in further challenges for those involved.Making the most of these developments can only reap benefits, as Hans Huttinga of Kerry Bioscience – Sheffield Pharma Ingredients portends, in Excipients Brace for a Market Transformation  
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RFID & ANTICOUNTERFEITING
A well-planned technology migration path maximises the life of a base label. Dr Andrew Dubner of 3M explores the value of programme investment, in Heavyweight Protection  
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Recent developments in RFID have lead to more widespread adoption, but does it lack the plug and play maturity that businesses expect from technology? Larry Klimczyk of Blackbay offers his advice on Entering the Mainstream  
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In Bespoke Code Reading – A Prescription for Less Confusion, Richard Laight and Charlie Plain-Jones at Absolute Vision explain how data matrix provides scope and opportunity for increased security and efficiency  
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Philippa Bruce of PRISYMID investigates how holographic imaging offers manufacturers better security for products, reputation and consumers, in Making It or Faking It  
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Counterfeit and gray market products continue to rise and the industry now needs to improve consumer confidence in prescription drugs. In Item Level RFID Tagging on Frequency, Joseph Pearson, from Texas Instruments Radio Frequency Identification Systems, gives his advice  
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Christian Puech at Packart examines the ways in which Track and Trace Benefits Pharma Packaging Printers, and claims digital document security is key to pharmaceutical print and packaging sector  
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Pharmapack 2010 supplement
In Outsourcing – Know the Risks, Juval Aviv of Interfor assesses the potentially disastrous perils of outsourcing; though it is becoming a given in the pharma industry, companies should not become complacent in managing risk  
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Recent clinical trials are more often than not globalised. Chris Wilson of Keats Healthcare talks to PMPS about the benefits of bespoke supply solutions on the Changing Clinical Trials Landscape  
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Sarah Gash at Bodycote Cirrus argues that conducting stability testing off-site achieves positive commercial results in the long term, in A Stabilised Position  
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IT and Logistics
The Weakest Link, by Abbes Kacimi and Gilles Labranque at Sofrigam, examines the role of the cold chain in the health products field, and analyses the level of risk of using cool pouches  
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Temperature-controlled requirements are rarely given the detailed attention they need, claims Geraint Thomas of Laminar Medica, in Keeping Your Cool Over Short-Distance Shipping  
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Jim Baxter at Maxiom Group considers the effect of outsourcing on each stage of the pharmaceutical supply chain, in All-Seeing Eye: Protecting the Supply Chain  
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LEAN MANUFACTURING
Lean Six Sigma can generate profit and growth in the companies that adopt it.Yet some are failing to make use of its full potential. Eight Lessons in Lean Six Sigma, by Bruno Ternon and Nico Alonzi of the George Group, demonstrate how to achieve major cost and performance improvements  
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WCI’s Marty Boom reviews the background of lean principles, in Lean Compliant Operations in Life Science, and finds that the integration of regulatory compliance with operational improvement is key to generating major improvements in pharma and biopharma operations  
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Take the Rough with the Smooth, advises Jo Smewing at Stable Micro Systems; advanced acoustic analysis and video playback instrumentation enable manufacturers to look at new dimensions in tablet texture  
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The development of prefilled syringes has resulted in better convenience and safety, but the demands are continuously rising, and standards of syringe safety devices need to meet them, explains Patrice Lewko of Rexam Pharma, in Safe and Sound  
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Jamal Temsamani and Claude Laruelle of CLL Pharma scrutinise the obstacle posed by the blood brain barrier, and the various resourceful ways in which it can be overcome, in Beating the Blood Brain Barrier  
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FLUID SYSTEM TECHNOLOGY
Swagelok Company’s Dave Simko compares miniature modular platforms and the new PAT initiative to traditional laboratory testing, in Taking the Lab to the Sample  
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Edited by
Robert Harris
Chief Technical Officer at Juniper Pharma Services
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